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Ultraviolet radiation drives mutations in a subset of mucosal melanomas
Although identified as the key environmental driver of common cutaneous melanoma, the role of ultraviolet radiation (UVR)-induced DNA damage in mucosal melanoma is poorly defined. We analyze 10 mucosal melanomas of conjunctival origin by whole genome sequencing and our data shows a predominance of U...
Autores principales: | Mundra, Piyushkumar A., Dhomen, Nathalie, Rodrigues, Manuel, Mikkelsen, Lauge Hjorth, Cassoux, Nathalie, Brooks, Kelly, Valpione, Sara, Reis-Filho, Jorge S., Heegaard, Steffen, Stern, Marc-Henri, Roman-Roman, Sergio, Marais, Richard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801393/ https://www.ncbi.nlm.nih.gov/pubmed/33431815 http://dx.doi.org/10.1038/s41467-020-20432-5 |
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