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Transformer neural network for protein-specific de novo drug generation as a machine translation problem
Drug discovery for a protein target is a very laborious, long and costly process. Machine learning approaches and, in particular, deep generative networks can substantially reduce development time and costs. However, the majority of methods imply prior knowledge of protein binders, their physicochem...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801439/ https://www.ncbi.nlm.nih.gov/pubmed/33432013 http://dx.doi.org/10.1038/s41598-020-79682-4 |