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No evidence for basigin/CD147 as a direct SARS-CoV-2 spike binding receptor

The spike protein of SARS-CoV-2 is known to enable viral invasion into human cells through direct binding to host receptors including ACE2. An alternate entry receptor for the virus was recently proposed to be basigin/CD147. These early studies have already prompted a clinical trial and multiple pub...

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Detalles Bibliográficos
Autores principales: Shilts, Jarrod, Crozier, Thomas W. M., Greenwood, Edward J. D., Lehner, Paul J., Wright, Gavin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801465/
https://www.ncbi.nlm.nih.gov/pubmed/33432067
http://dx.doi.org/10.1038/s41598-020-80464-1