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Cigarette smoke-induced impairment of autophagy in macrophages increases galectin-8 and inflammation

Cigarette smoke impairs autophagy, an intracellular protein degradation system, but the consequences of this defect have not been fully elucidated, especially in macrophages. Dysfunctional alveolar macrophages play an important role in chronic obstructive pulmonary disease (COPD). Here we show that...

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Detalles Bibliográficos
Autores principales: Kono, Yuta, Colley, Thomas, To, Masako, Papaioannou, Andriana I., Mercado, Nicolas, Baker, Jonathan R., To, Yasuo, Abe, Shinji, Haruki, Kosuke, Ito, Kazuhiro, Barnes, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801483/
https://www.ncbi.nlm.nih.gov/pubmed/33432024
http://dx.doi.org/10.1038/s41598-020-79848-0