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Cigarette smoke-induced impairment of autophagy in macrophages increases galectin-8 and inflammation
Cigarette smoke impairs autophagy, an intracellular protein degradation system, but the consequences of this defect have not been fully elucidated, especially in macrophages. Dysfunctional alveolar macrophages play an important role in chronic obstructive pulmonary disease (COPD). Here we show that...
Autores principales: | Kono, Yuta, Colley, Thomas, To, Masako, Papaioannou, Andriana I., Mercado, Nicolas, Baker, Jonathan R., To, Yasuo, Abe, Shinji, Haruki, Kosuke, Ito, Kazuhiro, Barnes, Peter J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801483/ https://www.ncbi.nlm.nih.gov/pubmed/33432024 http://dx.doi.org/10.1038/s41598-020-79848-0 |
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