Cargando…

Novel circRNA discovery in sheep shows evidence of high backsplice junction conservation

Circular RNAs (circRNAs) are covalently closed circular non-coding RNAs. Due to their structure, circRNAs are more stable and have longer half-lives than linear RNAs making them good candidates for disease biomarkers. Despite the scientific relevance of these molecules, the study of circRNAs in non-...

Descripción completa

Detalles Bibliográficos
Autores principales:	Varela-Martínez, Endika, Corsi, Giulia I., Anthon, Christian, Gorodkin, Jan, Jugo, Begoña M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801505/ https://www.ncbi.nlm.nih.gov/pubmed/33432020 http://dx.doi.org/10.1038/s41598-020-79781-2

Ejemplares similares

Engineering highly efficient backsplicing and translation of synthetic circRNAs
por: Meganck, Rita M., et al.
Publicado: (2021)

Identification of sheep lncRNAs related to the immune response to vaccines and aluminium adjuvants
por: Bilbao-Arribas, Martin, et al.
Publicado: (2021)

Identification and characterization of miRNAs in spleens of sheep subjected to repetitive vaccination
por: Varela-Martínez, Endika, et al.
Publicado: (2023)

Editorial: RNA Splicing and Backsplicing: Disease and Therapy
por: Asselta, Rosanna, et al.
Publicado: (2020)

Efficient backsplicing produces translatable circular mRNAs
por: Wang, Yang, et al.
Publicado: (2015)

CRISPRon/off: CRISPR/Cas9 on- and off-target gRNA design
por: Anthon, Christian, et al.
Publicado: (2022)

Letter to the editor: Testing on external independent datasets is necessary to corroborate machine learning model improvement
por: Corsi, Giulia Ilaria, et al.
Publicado: (2023)

The bioinformatics toolbox for circRNA discovery and analysis
por: Chen, Liang, et al.
Publicado: (2020)

Coding potential of circRNAs: new discoveries and challenges
por: Miao, Qingqing, et al.
Publicado: (2021)

The Characterization of GSDMB Splicing and Backsplicing Profiles Identifies Novel Isoforms and a Circular RNA That Are Dysregulated in Multiple Sclerosis
por: Cardamone, Giulia, et al.
Publicado: (2017)

From circRNAs to fusion circRNAs in hematological malignancies
por: Babin, Loelia, et al.
Publicado: (2021)

Retroviral Infections in Sheep and Goats: Small Ruminant Lentiviruses and Host Interaction
por: Larruskain, Amaia, et al.
Publicado: (2013)

circRNA-TBC1D4, circRNA-NAALAD2 and circRNA-TGFBR3: Selected Key circRNAs in Neuroblastoma and Their Associations with Clinical Features
por: Lin, Weihong, et al.
Publicado: (2021)

Expression analysis of lung miRNAs responding to ovine VM virus infection by RNA-seq
por: Bilbao-Arribas, Martin, et al.
Publicado: (2019)

Comprehensive Analysis of Differentially Expressed CircRNAs in the Ovaries of Low- and High-Fertility Sheep
por: Wang, Jinglei, et al.
Publicado: (2023)

CircPrimer: a software for annotating circRNAs and determining the specificity of circRNA primers
por: Zhong, Shanliang, et al.
Publicado: (2018)

Translation of CircRNAs
por: Pamudurti, Nagarjuna Reddy, et al.
Publicado: (2017)

Noncoding AUG circRNAs constitute an abundant and conserved subclass of circles
por: Stagsted, Lotte VW, et al.
Publicado: (2019)

Genome-Wide Identification of circRNAs in Pathogenic Basidiomycetous Yeast Cryptococcus neoformans Suggests Conserved circRNA Host Genes over Kingdoms
por: Huo, Liang, et al.
Publicado: (2018)

CircRNA Role and circRNA-Dependent Network (ceRNET) in Asthenozoospermia
por: Manfrevola, Francesco, et al.
Publicado: (2020)

Interactions of circRNAs with methylation: An important aspect of circRNA biogenesis and function
por: Zhang, Chunlei, et al.
Publicado: (2022)

Integrative transcriptome sequencing reveals extensive alternative trans-splicing and cis-backsplicing in human cells
por: Chuang, Trees-Juen, et al.
Publicado: (2018)

Internal Introns Promote Backsplicing to Generate Circular RNAs from Spinal Muscular Atrophy Gene
por: Luo, Diou, et al.
Publicado: (2022)

Comprehensive Expression Profiling Analysis of Pituitary Indicates that circRNA Participates in the Regulation of Sheep Estrus
por: Li, Xiaoyue, et al.
Publicado: (2019)

Differential Expression and Functional Analysis of CircRNA in the Ovaries of Low and High Fecundity Hanper Sheep
por: Liu, Aiju, et al.
Publicado: (2021)

CircPrimer 2.0: a software for annotating circRNAs and predicting translation potential of circRNAs
por: Zhong, Shanliang, et al.
Publicado: (2022)

Transcriptomic meta-analysis reveals unannotated long non-coding RNAs related to the immune response in sheep
por: Bilbao-Arribas, Martin, et al.
Publicado: (2022)

CircRNA-derived pseudogenes
por: Dong, Rui, et al.
Publicado: (2016)

The role of circRNAs in cancers
por: Zhu, Ling-Ping, et al.
Publicado: (2017)

The coding potential of circRNAs
por: Das, Aniruddha, et al.
Publicado: (2018)

CircRNA May Not Be “Circular”
por: Sun, Handong, et al.
Publicado: (2021)

CircRNAs in Tumor Radioresistance
por: Gao, Yining, et al.
Publicado: (2022)

Predicting circRNA-Disease Associations Based on circRNA Expression Similarity and Functional Similarity
por: Wang, Yongtian, et al.
Publicado: (2019)

Analysis of circRNAs and circRNA-associated competing endogenous RNA networks in β-thalassemia
por: Yang, Fang, et al.
Publicado: (2022)

Comprehensive CircRNA Profiling and Selection of Key CircRNAs Reveal the Potential Regulatory Roles of CircRNAs throughout Ovarian Development and Maturation in Cynoglossus semilaevis
por: Li, Jing, et al.
Publicado: (2021)

WebCircRNA: Classifying the Circular RNA Potential of Coding and Noncoding RNA
por: Pan, Xiaoyong, et al.
Publicado: (2018)

Identification and characterization of circRNAs in the skin during wool follicle development in Aohan fine wool sheep
por: Zhao, Ranran, et al.
Publicado: (2020)

PlantcircBase 7.0: Full-length transcripts and conservation of plant circRNAs
por: Xu, Xiaoxu, et al.
Publicado: (2022)

circRNA disease: a manually curated database of experimentally supported circRNA-disease associations
por: Zhao, Zheng, et al.
Publicado: (2018)

CircRNA expression profiles and circRNA-miRNA-mRNA crosstalk in allergic rhinitis()
por: Qiu, Chang-Yu, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_7kj9l0kl9694h63d6giceob2ld