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The role of the PIK3CA gene in the development and aging of the brain

The CLOVES syndrome is an overgrowth disease arising from mosaic activating somatic mutations in the PIK3CA gene. These mutations occur during fetal development producing malformation and overgrowth of a variety of tissues. It has recently been shown that treatment with low doses of a selective inhi...

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Detalles Bibliográficos
Autores principales: Xie, Shaozhen, Ni, Jing, Guo, Hanbing, Luu, Victor, Wang, Yanzhi, Zhao, Jean J., Roberts, Thomas M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801510/
https://www.ncbi.nlm.nih.gov/pubmed/33431926
http://dx.doi.org/10.1038/s41598-020-79416-6