Cargando…
Antibody neutralization of SARS-CoV-2 through ACE2 receptor mimicry
Understanding the mechanism for antibody neutralization of SARS-CoV-2 is critical for the development of effective therapeutics and vaccines. We recently isolated a large number of monoclonal antibodies from SARS-CoV-2 infected individuals. Here we select the top three most potent yet variable neutr...
Autores principales: | Ge, Jiwan, Wang, Ruoke, Ju, Bin, Zhang, Qi, Sun, Jing, Chen, Peng, Zhang, Senyan, Tian, Yuling, Shan, Sisi, Cheng, Lin, Zhou, Bing, Song, Shuo, Zhao, Juanjuan, Wang, Haiyan, Shi, Xuanling, Ding, Qiang, Liu, Lei, Zhao, Jincun, Zhang, Zheng, Wang, Xinquan, Zhang, Linqi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801515/ https://www.ncbi.nlm.nih.gov/pubmed/33431856 http://dx.doi.org/10.1038/s41467-020-20501-9 |
Ejemplares similares
-
Analysis of SARS-CoV-2 variant mutations reveals neutralization escape mechanisms and the ability to use ACE2 receptors from additional species
por: Wang, Ruoke, et al.
Publicado: (2021) -
Potent and protective IGHV3-53/3-66 public antibodies and their shared escape mutant on the spike of SARS-CoV-2
por: Zhang, Qi, et al.
Publicado: (2021) -
Broadly neutralizing and protective nanobodies against SARS-CoV-2 Omicron subvariants BA.1, BA.2, and BA.4/5 and diverse sarbecoviruses
por: Li, Mingxi, et al.
Publicado: (2022) -
SARS-CoV-2 Omicron Variants Reduce Antibody Neutralization and Acquire Usage of Mouse ACE2
por: Wang, Ruoke, et al.
Publicado: (2022) -
Infection with wild-type SARS-CoV-2 elicits broadly neutralizing and protective antibodies against omicron subvariants
por: Ju, Bin, et al.
Publicado: (2023)