Safe and effective aerosolization of in vitro transcribed mRNA to the respiratory tract epithelium of horses without a transfection agent

Vaccines and therapeutics using in vitro transcribed mRNA hold enormous potential for human and veterinary medicine. Transfection agents are widely considered to be necessary to protect mRNA and enhance transfection, but they add expense and raise concerns regarding quality control and safety. We fo...

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Detalles Bibliográficos
Autores principales: Legere, Rebecca M., Cohen, Noah D., Poveda, Cristina, Bray, Jocelyne M., Barhoumi, Rola, Szule, Joseph A., de la Concha-Bermejillo, Andrés, Bordin, Angela I., Pollet, Jeroen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801524/
https://www.ncbi.nlm.nih.gov/pubmed/33432084
http://dx.doi.org/10.1038/s41598-020-79855-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801524/
https://www.ncbi.nlm.nih.gov/pubmed/33432084
http://dx.doi.org/10.1038/s41598-020-79855-1

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