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Data-driven detection of subtype-specific differentially expressed genes
Among multiple subtypes of tissue or cell, subtype-specific differentially-expressed genes (SDEGs) are defined as being most-upregulated in only one subtype but not in any other. Detecting SDEGs plays a critical role in the molecular characterization and deconvolution of multicellular complex tissue...
Autores principales: | Chen, Lulu, Lu, Yingzhou, Wu, Chiung-Ting, Clarke, Robert, Yu, Guoqiang, Van Eyk, Jennifer E., Herrington, David M., Wang, Yue |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801594/ https://www.ncbi.nlm.nih.gov/pubmed/33432005 http://dx.doi.org/10.1038/s41598-020-79704-1 |
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