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Surface hydrophobics mediate functional dimerization of CYP121A1 of Mycobacterium tuberculosis

Tuberculosis is caused by the pathogenic bacterium Mycobacterium tuberculosis (Mtb) and remains the leading cause of death by infection world-wide. The Mtb genome encodes a disproportionate number of twenty cytochrome P450 enzymes, of which the essential enzyme cytochrome P450 121A1 (CYP121A1) remai...

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Detalles Bibliográficos
Autores principales:	Kumar, Amit, Campomizzi, Christopher S., Jay, Natalie, Ferguson, Shaun, Scheffler, Emelie-Jo, Lioi, James, Tu, Chengjian, Qu, Jun, Simons, Claire, Estrada, D. Fernando
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801616/ https://www.ncbi.nlm.nih.gov/pubmed/33431984 http://dx.doi.org/10.1038/s41598-020-79545-y

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