The TCR repertoire of α-synuclein-specific T cells in Parkinson’s disease is surprisingly diverse

The self-antigen α-synuclein (α-syn) was recently shown to be associated with Parkinson’s disease (PD). Here we mapped the T cell receptor (TCR) repertoire of α-syn-specific T cells from six PD patients. The self-antigen α-syn-specific repertoire was compared to the repertoire of T cells specific fo...

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Detalles Bibliográficos
Autores principales: Singhania, Akul, Pham, John, Dhanwani, Rekha, Frazier, April, Rezende Dutra, Juliana, Marder, Karen S., Phillips, Elizabeth, Mallal, Simon, Amara, Amy W., Standaert, David G., Sulzer, David, Peters, Bjoern, Sette, Alessandro, Lindestam Arlehamn, Cecilia S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801678/
https://www.ncbi.nlm.nih.gov/pubmed/33432042
http://dx.doi.org/10.1038/s41598-020-79726-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801678/
https://www.ncbi.nlm.nih.gov/pubmed/33432042
http://dx.doi.org/10.1038/s41598-020-79726-9

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