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LncRNA linc00312 suppresses radiotherapy resistance by targeting DNA-PKcs and impairing DNA damage repair in nasopharyngeal carcinoma

Radioresistance is the main obstacle in the clinical management of nasopharyngeal carcinoma (NPC). linc00312 is deregulated in a number of human cancers, including NPC. However, the detailed functions and underlying mechanisms of linc00312 in regulating radiosensitivity of NPC remains unknown. In th...

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Detalles Bibliográficos
Autores principales: Guo, Zhen, Wang, You-Hong, Xu, Heng, Yuan, Chun-Su, Zhou, Hong-Hao, Huang, Wei-Hua, Wang, Hui, Zhang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801696/
https://www.ncbi.nlm.nih.gov/pubmed/33431817
http://dx.doi.org/10.1038/s41419-020-03302-2

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