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Longitudinal Associations of Blood Phosphorylated Tau181 and Neurofilament Light Chain With Neurodegeneration in Alzheimer Disease
IMPORTANCE: Plasma phosphorylated tau at threonine 181 (p-tau181) has been proposed as an easily accessible biomarker for the detection of Alzheimer disease (AD) pathology, but its ability to monitor disease progression in AD remains unclear. OBJECTIVE: To study the potential of longitudinal plasma...
Autores principales: | Moscoso, Alexis, Grothe, Michel J., Ashton, Nicholas J., Karikari, Thomas K., Lantero Rodríguez, Juan, Snellman, Anniina, Suárez-Calvet, Marc, Blennow, Kaj, Zetterberg, Henrik, Schöll, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Medical Association
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7802009/ https://www.ncbi.nlm.nih.gov/pubmed/33427873 http://dx.doi.org/10.1001/jamaneurol.2020.4986 |
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