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Impact of Platelet Count in Retinopathy of Prematurity

OBJECTIVES: The aim of the study was to investigate the risk factors for retinopathy of prematurity (ROP), including platelet count. MATERIALS AND METHODS: This retrospective study analyzed 137 infants in 3 subgroups: no ROP; mild ROP, and severe ROP requiring laser treatment (type 1 ROP). A retrosp...

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Autores principales: Şahinoğlu Keşkek, Nedime, Gülcan, Hande, Yılmaz, Gürsel, Akkoyun, İmren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7802096/
https://www.ncbi.nlm.nih.gov/pubmed/33389935
http://dx.doi.org/10.4274/tjo.galenos.2020.01058
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author Şahinoğlu Keşkek, Nedime
Gülcan, Hande
Yılmaz, Gürsel
Akkoyun, İmren
author_facet Şahinoğlu Keşkek, Nedime
Gülcan, Hande
Yılmaz, Gürsel
Akkoyun, İmren
author_sort Şahinoğlu Keşkek, Nedime
collection PubMed
description OBJECTIVES: The aim of the study was to investigate the risk factors for retinopathy of prematurity (ROP), including platelet count. MATERIALS AND METHODS: This retrospective study analyzed 137 infants in 3 subgroups: no ROP; mild ROP, and severe ROP requiring laser treatment (type 1 ROP). A retrospective review of records was performed and statistical analysis of possible risk factors for ROP including platelet count was evaluated by using logistic regression. RESULTS: Birth weight (BW), gestational age (GA), and low platelet count in the first week after birth were significant risk factors for developing ROP (p=0.038, 0.02, and 0.004, respectively). BW, GA, ventilation, and lower platelet count were associated with progression to type 1 ROP (p=0.004; 0.027, and 0.021, respectively). CONCLUSION: Lower platelet count in the first week after birth is a risk factor for ROP development in addition to the previously established factors of ventilation need, low BW, and low GA.
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spelling pubmed-78020962021-01-21 Impact of Platelet Count in Retinopathy of Prematurity Şahinoğlu Keşkek, Nedime Gülcan, Hande Yılmaz, Gürsel Akkoyun, İmren Turk J Ophthalmol Original Article OBJECTIVES: The aim of the study was to investigate the risk factors for retinopathy of prematurity (ROP), including platelet count. MATERIALS AND METHODS: This retrospective study analyzed 137 infants in 3 subgroups: no ROP; mild ROP, and severe ROP requiring laser treatment (type 1 ROP). A retrospective review of records was performed and statistical analysis of possible risk factors for ROP including platelet count was evaluated by using logistic regression. RESULTS: Birth weight (BW), gestational age (GA), and low platelet count in the first week after birth were significant risk factors for developing ROP (p=0.038, 0.02, and 0.004, respectively). BW, GA, ventilation, and lower platelet count were associated with progression to type 1 ROP (p=0.004; 0.027, and 0.021, respectively). CONCLUSION: Lower platelet count in the first week after birth is a risk factor for ROP development in addition to the previously established factors of ventilation need, low BW, and low GA. Galenos Publishing 2020-12 2020-12-29 /pmc/articles/PMC7802096/ /pubmed/33389935 http://dx.doi.org/10.4274/tjo.galenos.2020.01058 Text en © Copyright 2020 by Turkish Ophthalmological Association | Turkish Journal of Ophthalmology, published by Galenos Publishing House. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Şahinoğlu Keşkek, Nedime
Gülcan, Hande
Yılmaz, Gürsel
Akkoyun, İmren
Impact of Platelet Count in Retinopathy of Prematurity
title Impact of Platelet Count in Retinopathy of Prematurity
title_full Impact of Platelet Count in Retinopathy of Prematurity
title_fullStr Impact of Platelet Count in Retinopathy of Prematurity
title_full_unstemmed Impact of Platelet Count in Retinopathy of Prematurity
title_short Impact of Platelet Count in Retinopathy of Prematurity
title_sort impact of platelet count in retinopathy of prematurity
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7802096/
https://www.ncbi.nlm.nih.gov/pubmed/33389935
http://dx.doi.org/10.4274/tjo.galenos.2020.01058
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