Cargando…

Primary Anaplastic Ganglioglioma of the Temporal Lobe With Brainstem Involvement: A Case Report and Literature Review

Anaplastic ganglioglioma (AGG) is a rare and aggressive counterpart of the more benign and frequently encountered glioma. Herein, we present a 21-year-old female who presented with episodes of total amnesia and complex partial seizures, which led to the diagnosis of AGG localized to the medial tempo...

Descripción completa

Detalles Bibliográficos
Autores principales: Klimko, Artsiom, Dandes, Mariana, Paslaru, Francesca, Giovani, Andrei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7802110/
https://www.ncbi.nlm.nih.gov/pubmed/33447489
http://dx.doi.org/10.7759/cureus.12060
_version_ 1783635704396382208
author Klimko, Artsiom
Dandes, Mariana
Paslaru, Francesca
Giovani, Andrei
author_facet Klimko, Artsiom
Dandes, Mariana
Paslaru, Francesca
Giovani, Andrei
author_sort Klimko, Artsiom
collection PubMed
description Anaplastic ganglioglioma (AGG) is a rare and aggressive counterpart of the more benign and frequently encountered glioma. Herein, we present a 21-year-old female who presented with episodes of total amnesia and complex partial seizures, which led to the diagnosis of AGG localized to the medial temporal lobe. She subsequently underwent surgical cytoreduction of the tumor three times with adjuvant chemoradiotherapy. The extent of resection throughout the surgeries was hindered by the extension of the tumor to critical neurovascular structures; during the last surgery, invasion into the pons was noted, which posed a significant clinical challenge.
format Online
Article
Text
id pubmed-7802110
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Cureus
record_format MEDLINE/PubMed
spelling pubmed-78021102021-01-13 Primary Anaplastic Ganglioglioma of the Temporal Lobe With Brainstem Involvement: A Case Report and Literature Review Klimko, Artsiom Dandes, Mariana Paslaru, Francesca Giovani, Andrei Cureus Neurology Anaplastic ganglioglioma (AGG) is a rare and aggressive counterpart of the more benign and frequently encountered glioma. Herein, we present a 21-year-old female who presented with episodes of total amnesia and complex partial seizures, which led to the diagnosis of AGG localized to the medial temporal lobe. She subsequently underwent surgical cytoreduction of the tumor three times with adjuvant chemoradiotherapy. The extent of resection throughout the surgeries was hindered by the extension of the tumor to critical neurovascular structures; during the last surgery, invasion into the pons was noted, which posed a significant clinical challenge. Cureus 2020-12-13 /pmc/articles/PMC7802110/ /pubmed/33447489 http://dx.doi.org/10.7759/cureus.12060 Text en Copyright © 2020, Klimko et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Neurology
Klimko, Artsiom
Dandes, Mariana
Paslaru, Francesca
Giovani, Andrei
Primary Anaplastic Ganglioglioma of the Temporal Lobe With Brainstem Involvement: A Case Report and Literature Review
title Primary Anaplastic Ganglioglioma of the Temporal Lobe With Brainstem Involvement: A Case Report and Literature Review
title_full Primary Anaplastic Ganglioglioma of the Temporal Lobe With Brainstem Involvement: A Case Report and Literature Review
title_fullStr Primary Anaplastic Ganglioglioma of the Temporal Lobe With Brainstem Involvement: A Case Report and Literature Review
title_full_unstemmed Primary Anaplastic Ganglioglioma of the Temporal Lobe With Brainstem Involvement: A Case Report and Literature Review
title_short Primary Anaplastic Ganglioglioma of the Temporal Lobe With Brainstem Involvement: A Case Report and Literature Review
title_sort primary anaplastic ganglioglioma of the temporal lobe with brainstem involvement: a case report and literature review
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7802110/
https://www.ncbi.nlm.nih.gov/pubmed/33447489
http://dx.doi.org/10.7759/cureus.12060
work_keys_str_mv AT klimkoartsiom primaryanaplasticgangliogliomaofthetemporallobewithbrainsteminvolvementacasereportandliteraturereview
AT dandesmariana primaryanaplasticgangliogliomaofthetemporallobewithbrainsteminvolvementacasereportandliteraturereview
AT paslarufrancesca primaryanaplasticgangliogliomaofthetemporallobewithbrainsteminvolvementacasereportandliteraturereview
AT giovaniandrei primaryanaplasticgangliogliomaofthetemporallobewithbrainsteminvolvementacasereportandliteraturereview