Successful pregnancy after operation in an infertile woman caused by luteinizing hormone-secreting pituitary adenoma: case report and literature review

BACKGROUND: Functional gonadotroph adenomas (FGAs) are rare adenomas that most commonly secrete FSH. However, solitary LH-secreting pituitary adenomas are unusual. CASE PRESENTATION: A 30-year-old woman with elevated LH and normal FSH presented with inability to conceive. An MRI revealed an enlarged...

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Autores principales: Zhang, Yi, Chen, Cheng, Lin, Min, Deng, Kan, Zhu, Huijuan, Ma, Wenbin, Pan, Hui, Wang, Renzhi, Yao, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7802169/
https://www.ncbi.nlm.nih.gov/pubmed/33435923
http://dx.doi.org/10.1186/s12902-020-00677-3
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author Zhang, Yi
Chen, Cheng
Lin, Min
Deng, Kan
Zhu, Huijuan
Ma, Wenbin
Pan, Hui
Wang, Renzhi
Yao, Yong
author_facet Zhang, Yi
Chen, Cheng
Lin, Min
Deng, Kan
Zhu, Huijuan
Ma, Wenbin
Pan, Hui
Wang, Renzhi
Yao, Yong
author_sort Zhang, Yi
collection PubMed
description BACKGROUND: Functional gonadotroph adenomas (FGAs) are rare adenomas that most commonly secrete FSH. However, solitary LH-secreting pituitary adenomas are unusual. CASE PRESENTATION: A 30-year-old woman with elevated LH and normal FSH presented with inability to conceive. An MRI revealed an enlarged sella turcica and an intrasellar mass. Treatment with transsphenoidal resection led to normalization of LH and estradiol, as well as successful pregnancy. And we reviewed 6 cases of LH-secreting pituitary adenomas from 1981 to 2020. CONCLUSIONS: Our case is unique because of the LH-secreting pituitary adenoma without FSH hypersecretion. This case indicates that pituitary adenoma should be considered when other diseases causing infertility have been excluded.
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spelling pubmed-78021692021-01-12 Successful pregnancy after operation in an infertile woman caused by luteinizing hormone-secreting pituitary adenoma: case report and literature review Zhang, Yi Chen, Cheng Lin, Min Deng, Kan Zhu, Huijuan Ma, Wenbin Pan, Hui Wang, Renzhi Yao, Yong BMC Endocr Disord Case Report BACKGROUND: Functional gonadotroph adenomas (FGAs) are rare adenomas that most commonly secrete FSH. However, solitary LH-secreting pituitary adenomas are unusual. CASE PRESENTATION: A 30-year-old woman with elevated LH and normal FSH presented with inability to conceive. An MRI revealed an enlarged sella turcica and an intrasellar mass. Treatment with transsphenoidal resection led to normalization of LH and estradiol, as well as successful pregnancy. And we reviewed 6 cases of LH-secreting pituitary adenomas from 1981 to 2020. CONCLUSIONS: Our case is unique because of the LH-secreting pituitary adenoma without FSH hypersecretion. This case indicates that pituitary adenoma should be considered when other diseases causing infertility have been excluded. BioMed Central 2021-01-12 /pmc/articles/PMC7802169/ /pubmed/33435923 http://dx.doi.org/10.1186/s12902-020-00677-3 Text en © The Author(s) 2021 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
Zhang, Yi
Chen, Cheng
Lin, Min
Deng, Kan
Zhu, Huijuan
Ma, Wenbin
Pan, Hui
Wang, Renzhi
Yao, Yong
Successful pregnancy after operation in an infertile woman caused by luteinizing hormone-secreting pituitary adenoma: case report and literature review
title Successful pregnancy after operation in an infertile woman caused by luteinizing hormone-secreting pituitary adenoma: case report and literature review
title_full Successful pregnancy after operation in an infertile woman caused by luteinizing hormone-secreting pituitary adenoma: case report and literature review
title_fullStr Successful pregnancy after operation in an infertile woman caused by luteinizing hormone-secreting pituitary adenoma: case report and literature review
title_full_unstemmed Successful pregnancy after operation in an infertile woman caused by luteinizing hormone-secreting pituitary adenoma: case report and literature review
title_short Successful pregnancy after operation in an infertile woman caused by luteinizing hormone-secreting pituitary adenoma: case report and literature review
title_sort successful pregnancy after operation in an infertile woman caused by luteinizing hormone-secreting pituitary adenoma: case report and literature review
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7802169/
https://www.ncbi.nlm.nih.gov/pubmed/33435923
http://dx.doi.org/10.1186/s12902-020-00677-3
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