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Maternal folic acid impacts DNA methylation profile in male rat offspring implicated in neurodevelopment and learning/memory abilities
BACKGROUND: Periconceptional folic acid (FA) supplementation not only reduces the incidence of neural tube defects, but also improves cognitive performances in offspring. However, the genes or pathways that are epigenetically regulated by FA in neurodevelopment were rarely reported. METHODS: To eluc...
Autores principales: | Wang, Xinyan, Li, Zhenshu, Zhu, Yun, Yan, Jing, Liu, Huan, Huang, Guowei, Li, Wen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7802276/ https://www.ncbi.nlm.nih.gov/pubmed/33430764 http://dx.doi.org/10.1186/s12263-020-00681-1 |
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