Mesenchymal stem cells genetically engineered to express platelet-derived growth factor and heme oxygenase-1 ameliorate osteoarthritis in a canine model

BACKGROUND: Mesenchymal stem cells (MSCs) are used for the treatment of osteoarthritis (OA), and MSC genetic engineering is expected to enhance cartilage repair. Here, we aimed to investigate the effect of MSCs overexpressing platelet-derived growth factor (PDGF) or heme oxygenase-1 (HO-1) in chondr...

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Detalles Bibliográficos
Autores principales: Oh, Jiwon, Son, Yeon Sung, Kim, Wan Hee, Kwon, Oh-Kyeong, Kang, Byung-Jae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7802278/
https://www.ncbi.nlm.nih.gov/pubmed/33430899
http://dx.doi.org/10.1186/s13018-020-02178-4

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