Cargando…

Adhesion G protein-coupled receptor, ELTD1, is a potential therapeutic target for retinoblastoma migration and invasion

BACKGROUND: Prognosis for pediatric metastatic Retinoblastoma (Rb) is poor and current therapies are limited by high systemic toxicity rates and insufficient therapeutic efficacy for metastatic Rb. Tumor dissemination to the brain is promoted by the heterogeneous adhesive and invasive properties of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Guihurt Santiago, Jonathan, Burgos-Tirado, Neikelyn, Lafontaine, Daniella Dorta, Mendoza Sierra, José C., Camacho, Roberto Herrera, Vecchini Rodríguez, Clara M., Morales-Tirado, Vanessa, Flores-Otero, Jacqueline
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7802354/ https://www.ncbi.nlm.nih.gov/pubmed/33430814 http://dx.doi.org/10.1186/s12885-020-07768-3

Ejemplares similares

Targeting the Platelet-Derived Growth Factor-beta Stimulatory Circuitry to Control Retinoblastoma Seeds
por: Goldsmith, Zachary K., et al.
Publicado: (2018)

ELTD1—An Emerging Silent Actor in Cancer Drama Play
por: Sevastre, Ani-Simona, et al.
Publicado: (2021)

ELTD1 Function in Hepatocellular Carcinoma is Carcinoma-Associated Fibroblast-Dependent
por: Kan, Anna, et al.
Publicado: (2018)

Augmented Cardiac Hypertrophy in Response to Pressure Overload in Mice Lacking ELTD1
por: Xiao, Jinfeng, et al.
Publicado: (2012)

ELTD1 promotes invasion and metastasis by activating MMP2 in colorectal cancer
por: Sun, Jiawei, et al.
Publicado: (2021)

ELTD1 Activation Induces an Endothelial-EMT Transition to a Myofibroblast Phenotype
por: Sheldon, Helen, et al.
Publicado: (2021)

ELTD1 as a multi-focal target for malignant gliomas: preclinical studies
por: Zalles, Michelle, et al.
Publicado: (2021)

Elevated expression of the adhesion GPCR ADGRL4/ELTD1 promotes endothelial sprouting angiogenesis without activating canonical GPCR signalling
por: Favara, David M., et al.
Publicado: (2021)

ADGRL4/ELTD1 is a highly conserved angiogenesis-associated orphan adhesion GPCR that emerged with the first vertebrates and comprises 3 evolutionary variants
por: Favara, David M., et al.
Publicado: (2019)

Tumor endothelial ELTD1 as a predictive marker for treatment of renal cancer patients with sunitinib
por: Niinivirta, Marjut, et al.
Publicado: (2020)

Real-time visualization of phagosomal pH manipulation by Cryptococcus neoformans in an immune signal-dependent way
por: Santiago-Burgos, Emmanuel J., et al.
Publicado: (2022)

Inhibition of MMP-2 and MMP-9 decreases cellular migration, and angiogenesis in in vitro models of retinoblastoma
por: Webb, Anderson H., et al.
Publicado: (2017)

Optimized monoclonal antibody treatment against ELTD1 for GBM in a G55 xenograft mouse model
por: Zalles, Michelle, et al.
Publicado: (2019)

Assessment of an scFv Antibody Fragment Against ELTD1 in a G55 Glioblastoma Xenograft Model()()
por: Zalles, Michelle, et al.
Publicado: (2020)

ELTD1 deletion reduces vascular abnormality and improves T-cell recruitment after PD-1 blockade in glioma
por: Huang, Hua, et al.
Publicado: (2021)

A tale of two multi‐focal therapies for glioblastoma: An antibody targeting ELTD1 and nitrone‐based OKN‐007
por: Zalles, Michelle, et al.
Publicado: (2021)

ELTD1 facilitates glioma proliferation, migration and invasion by activating JAK/STAT3/HIF-1α signaling axis
por: Li, Junjun, et al.
Publicado: (2019)

L1 increases adhesion-mediated proliferation and chemoresistance of retinoblastoma
por: Jo, Dong Hyun, et al.
Publicado: (2017)

mSphere of Influence: the Power of Yeast Genetics Still Going Strong!
por: Santiago-Tirado, Felipe H.
Publicado: (2019)

"Retinoblastoma" : revisión bibliográfica y presentación de un caso clínico/
por: Mendoza Barradas, María del Rosario
Publicado: (1992)

A Core Human Primary Tumor Angiogenesis Signature Identifies the Endothelial Orphan Receptor ELTD1 as a Key Regulator of Angiogenesis
por: Masiero, Massimo, et al.
Publicado: (2013)

Developmental vascular remodeling defects and postnatal kidney failure in mice lacking Gpr116 (Adgrf5) and Eltd1 (Adgrl4)
por: Lu, Shun, et al.
Publicado: (2017)

ADGRL4/ELTD1 Silencing in Endothelial Cells Induces ACLY and SLC25A1 and Alters the Cellular Metabolic Profile
por: Favara, David M., et al.
Publicado: (2019)

ELTD1 Promotes Gastric Cancer Cell Proliferation, Invasion and Epithelial–Mesenchymal Transition Through MAPK/ERK Signaling by Regulating CSK
por: Sun, Bo, et al.
Publicado: (2021)

PRELP Regulates Cell–Cell Adhesion and EMT and Inhibits Retinoblastoma Progression
por: Hopkins, Jack, et al.
Publicado: (2022)

Regulatory Immunotherapy in Bone Marrow Transplantation
por: Morales-Tirado, Vanessa, et al.
Publicado: (2012)

A Role for the Retinoblastoma Protein As a Regulator of Mouse Osteoblast Cell Adhesion: Implications for Osteogenesis and Osteosarcoma Formation
por: Sosa-García, Bernadette, et al.
Publicado: (2010)

Retinoblastoma Protein Paralogs and Tumor Suppression
por: Flores, Mauricio, et al.
Publicado: (2022)

False friends: Phagocytes as Trojan horses in microbial brain infections
por: Santiago-Tirado, Felipe H., et al.
Publicado: (2017)

A year in review (2022): Modulators and COVID19, the story goes on…
por: Dillenhoefer, Stefanie, et al.
Publicado: (2023)

Uveal metastases in the mid-southeastern United States: a single-institution experience
por: King, Benjamin A, et al.
Publicado: (2018)

Retinoblastoma
por: Martínez Cabrera, Guadalupe
Publicado: (1998)

Retinoblastoma
por: Aerts, Isabelle, et al.
Publicado: (2006)

Target-specific delivery of doxorubicin to retinoblastoma using epithelial cell adhesion molecule aptamer
por: Subramanian, Nithya, et al.
Publicado: (2012)

Retinoblastoma: Review and new insights
por: Cruz-Gálvez, Claudia Carolina, et al.
Publicado: (2022)

The Retinoblastoma Tumor Suppressor Transcriptionally Represses Pak1 in Osteoblasts
por: Sosa-García, Bernadette, et al.
Publicado: (2015)

Yeast formin Bni1p has multiple localization regions that function in polarized growth and spindle orientation
por: Liu, Wenyu, et al.
Publicado: (2012)

Pioglitazone alters monocyte populations and stimulates recent thymic emigrants in the BBDZR/Wor type 2 diabetes rat model
por: Gao, Bradley T., et al.
Publicado: (2015)

Natural killer cells and pigment epithelial-derived factor control the infiltrative and nodular growth of hepatic metastases in an Orthotopic murine model of ocular melanoma
por: Jones, Nyasia M., et al.
Publicado: (2019)

La nacionalización de la banca privada en México /
por: Tirado, Manlio
Publicado: (1982)

Cannot write session to /tmp/vufind_sessions/sess_6k1l24fn3unt67okqgjdvs74q2