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Granular detail of β cell structures for insulin secretion
Pancreatic β cells secrete insulin in response to increased glucose concentrations. Müller et al. (2021. J. Cell Biol. https://doi.org/10.1083/jcb.202010039) use 3D FIB-SEM to study the architecture of these cells and to elucidate how glucose stimulation remodels microtubules to control insulin secr...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Rockefeller University Press
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7802365/ https://www.ncbi.nlm.nih.gov/pubmed/33427875 http://dx.doi.org/10.1083/jcb.202012082 |
Sumario: | Pancreatic β cells secrete insulin in response to increased glucose concentrations. Müller et al. (2021. J. Cell Biol. https://doi.org/10.1083/jcb.202010039) use 3D FIB-SEM to study the architecture of these cells and to elucidate how glucose stimulation remodels microtubules to control insulin secretory granule exocytosis. |
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