Stem cell origins of JMML

In this issue of JEM, Louka et al. (https://doi.org/10.1084/jem.20180853) report that leukemia stem cells lie within the phenotypic hematopoietic stem cell and progenitor cell compartments in juvenile myelomonocytic leukemia (JMML). Furthermore, they identify several candidate biomarker/therapeutic...

Descripción completa

Detalles Bibliográficos
Autores principales: Sundaravel, Sriram, Steidl, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Insights
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7802372/
https://www.ncbi.nlm.nih.gov/pubmed/33427877
http://dx.doi.org/10.1084/jem.20202152
_version_ 1783635759742320640
author Sundaravel, Sriram
Steidl, Ulrich
author_facet Sundaravel, Sriram
Steidl, Ulrich
author_sort Sundaravel, Sriram
collection PubMed
description In this issue of JEM, Louka et al. (https://doi.org/10.1084/jem.20180853) report that leukemia stem cells lie within the phenotypic hematopoietic stem cell and progenitor cell compartments in juvenile myelomonocytic leukemia (JMML). Furthermore, they identify several candidate biomarker/therapeutic targets, such as CD96 and SLC2A1, that are of translational significance in JMML.
format Online
Article
Text
id pubmed-7802372
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Rockefeller University Press
record_format MEDLINE/PubMed
spelling pubmed-78023722021-08-01 Stem cell origins of JMML Sundaravel, Sriram Steidl, Ulrich J Exp Med Insights In this issue of JEM, Louka et al. (https://doi.org/10.1084/jem.20180853) report that leukemia stem cells lie within the phenotypic hematopoietic stem cell and progenitor cell compartments in juvenile myelomonocytic leukemia (JMML). Furthermore, they identify several candidate biomarker/therapeutic targets, such as CD96 and SLC2A1, that are of translational significance in JMML. Rockefeller University Press 2021-01-11 /pmc/articles/PMC7802372/ /pubmed/33427877 http://dx.doi.org/10.1084/jem.20202152 Text en © 2021 Sundaravel and Steidl http://www.rupress.org/terms/https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Insights
Sundaravel, Sriram
Steidl, Ulrich
Stem cell origins of JMML
title Stem cell origins of JMML
title_full Stem cell origins of JMML
title_fullStr Stem cell origins of JMML
title_full_unstemmed Stem cell origins of JMML
title_short Stem cell origins of JMML
title_sort stem cell origins of jmml
topic Insights
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7802372/
https://www.ncbi.nlm.nih.gov/pubmed/33427877
http://dx.doi.org/10.1084/jem.20202152
work_keys_str_mv AT sundaravelsriram stemcelloriginsofjmml
AT steidlulrich stemcelloriginsofjmml

Ejemplares similares