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Physics of viral dynamics

Viral capsids are often regarded as inert structural units, but in actuality they display fascinating dynamics during different stages of their life cycle. With the advent of single-particle approaches and high-resolution techniques, it is now possible to scrutinize viral dynamics during and after t...

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Detalles Bibliográficos
Autores principales: Bruinsma, Robijn F., Wuite, Gijs J. L., Roos, Wouter H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7802615/
https://www.ncbi.nlm.nih.gov/pubmed/33728406
http://dx.doi.org/10.1038/s42254-020-00267-1
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author Bruinsma, Robijn F.
Wuite, Gijs J. L.
Roos, Wouter H.
author_facet Bruinsma, Robijn F.
Wuite, Gijs J. L.
Roos, Wouter H.
author_sort Bruinsma, Robijn F.
collection PubMed
description Viral capsids are often regarded as inert structural units, but in actuality they display fascinating dynamics during different stages of their life cycle. With the advent of single-particle approaches and high-resolution techniques, it is now possible to scrutinize viral dynamics during and after their assembly and during the subsequent development pathway into infectious viruses. In this Review, the focus is on the dynamical properties of viruses, the different physical virology techniques that are being used to study them, and the physical concepts that have been developed to describe viral dynamics.
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spelling pubmed-78026152021-01-13 Physics of viral dynamics Bruinsma, Robijn F. Wuite, Gijs J. L. Roos, Wouter H. Nat Rev Phys Review Article Viral capsids are often regarded as inert structural units, but in actuality they display fascinating dynamics during different stages of their life cycle. With the advent of single-particle approaches and high-resolution techniques, it is now possible to scrutinize viral dynamics during and after their assembly and during the subsequent development pathway into infectious viruses. In this Review, the focus is on the dynamical properties of viruses, the different physical virology techniques that are being used to study them, and the physical concepts that have been developed to describe viral dynamics. Nature Publishing Group UK 2021-01-12 2021 /pmc/articles/PMC7802615/ /pubmed/33728406 http://dx.doi.org/10.1038/s42254-020-00267-1 Text en © Springer Nature Limited 2021 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Review Article
Bruinsma, Robijn F.
Wuite, Gijs J. L.
Roos, Wouter H.
Physics of viral dynamics
title Physics of viral dynamics
title_full Physics of viral dynamics
title_fullStr Physics of viral dynamics
title_full_unstemmed Physics of viral dynamics
title_short Physics of viral dynamics
title_sort physics of viral dynamics
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7802615/
https://www.ncbi.nlm.nih.gov/pubmed/33728406
http://dx.doi.org/10.1038/s42254-020-00267-1
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