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Granulomatosis with polyangiitis presenting with unilateral facial nerve palsy and nasal septum perforation

Granulomatosis with polyangiitis (GPA) is a necrotising vasculitis of unknown cause that has several systemic manifestations. The disease is characterised by the classical triad involving acute inflammation of the upper and lower respiratory tracts with renal involvement. However, the disease pathol...

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Autores principales: Zaeri, Bandar, Khan, Soha, Hegazy, Asmaa, Al Ghanim, Nayef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7802726/
https://www.ncbi.nlm.nih.gov/pubmed/33431530
http://dx.doi.org/10.1136/bcr-2020-236469
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author Zaeri, Bandar
Khan, Soha
Hegazy, Asmaa
Al Ghanim, Nayef
author_facet Zaeri, Bandar
Khan, Soha
Hegazy, Asmaa
Al Ghanim, Nayef
author_sort Zaeri, Bandar
collection PubMed
description Granulomatosis with polyangiitis (GPA) is a necrotising vasculitis of unknown cause that has several systemic manifestations. The disease is characterised by the classical triad involving acute inflammation of the upper and lower respiratory tracts with renal involvement. However, the disease pathology can involve the central nervous system. This case report presents a case of GPA with facial nerve palsy as the first manifestation of the disease, which has been rarely reported in the medical literature.
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spelling pubmed-78027262021-01-21 Granulomatosis with polyangiitis presenting with unilateral facial nerve palsy and nasal septum perforation Zaeri, Bandar Khan, Soha Hegazy, Asmaa Al Ghanim, Nayef BMJ Case Rep Case Report Granulomatosis with polyangiitis (GPA) is a necrotising vasculitis of unknown cause that has several systemic manifestations. The disease is characterised by the classical triad involving acute inflammation of the upper and lower respiratory tracts with renal involvement. However, the disease pathology can involve the central nervous system. This case report presents a case of GPA with facial nerve palsy as the first manifestation of the disease, which has been rarely reported in the medical literature. BMJ Publishing Group 2021-01-11 /pmc/articles/PMC7802726/ /pubmed/33431530 http://dx.doi.org/10.1136/bcr-2020-236469 Text en © BMJ Publishing Group Limited 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/ http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.
spellingShingle Case Report
Zaeri, Bandar
Khan, Soha
Hegazy, Asmaa
Al Ghanim, Nayef
Granulomatosis with polyangiitis presenting with unilateral facial nerve palsy and nasal septum perforation
title Granulomatosis with polyangiitis presenting with unilateral facial nerve palsy and nasal septum perforation
title_full Granulomatosis with polyangiitis presenting with unilateral facial nerve palsy and nasal septum perforation
title_fullStr Granulomatosis with polyangiitis presenting with unilateral facial nerve palsy and nasal septum perforation
title_full_unstemmed Granulomatosis with polyangiitis presenting with unilateral facial nerve palsy and nasal septum perforation
title_short Granulomatosis with polyangiitis presenting with unilateral facial nerve palsy and nasal septum perforation
title_sort granulomatosis with polyangiitis presenting with unilateral facial nerve palsy and nasal septum perforation
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7802726/
https://www.ncbi.nlm.nih.gov/pubmed/33431530
http://dx.doi.org/10.1136/bcr-2020-236469
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