Serial cryoFIB/SEM Reveals Cytoarchitectural Disruptions in Leigh Syndrome Patient Cells

The advancement of serial cryoFIB/SEM offers an opportunity to study large volumes of near-native, fully hydrated frozen cells and tissues at voxel sizes of 10 nm and below. We explored this capability for pathologic characterization of vitrified human patient cells by developing and optimizing a se...

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Detalles Bibliográficos
Autores principales: Zhu, Yanan, Sun, Dapeng, Schertel, Andreas, Ning, Jiying, Fu, Xiaofeng, Gwo, Pam Pam, Watson, Alan M., Zanetti-Domingues, Laura C., Martin-Fernandez, Marisa L., Freyberg, Zachary, Zhang, Peijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Short Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7802768/
https://www.ncbi.nlm.nih.gov/pubmed/33096015
http://dx.doi.org/10.1016/j.str.2020.10.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7802768/
https://www.ncbi.nlm.nih.gov/pubmed/33096015
http://dx.doi.org/10.1016/j.str.2020.10.003

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