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Non-Hodgkins lymphoma – A case report and review of literature
Lymphomas are solid tumors of the immune system and include 14% of all head and neck malignancies. Non-Hodgkin lymphomas (NHLs) are a heterogeneous group of lymphoproliferative disorders originating in B-, T-, or natural killer T-cells. They have a wide range of histological appearances and clinical...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7802842/ https://www.ncbi.nlm.nih.gov/pubmed/33456242 http://dx.doi.org/10.4103/jomfp.JOMFP_271_19 |
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author | Singaraju, Sasidhar Patel, Shubham Sharma, Ashish Singaraju, Medhini |
author_facet | Singaraju, Sasidhar Patel, Shubham Sharma, Ashish Singaraju, Medhini |
author_sort | Singaraju, Sasidhar |
collection | PubMed |
description | Lymphomas are solid tumors of the immune system and include 14% of all head and neck malignancies. Non-Hodgkin lymphomas (NHLs) are a heterogeneous group of lymphoproliferative disorders originating in B-, T-, or natural killer T-cells. They have a wide range of histological appearances and clinical features at presentation, which can make diagnosis difficult. A 58-year-old male patient presented with a 1-month history of swelling in the upper right back tooth region, which developed after extraction. On intraoral examination, there was small nodular lesion proliferation from the extracted socket. Biopsy specimen on histological examination revealed sheets of small round cells with hyperchromatic nucleus resembling lymphoblast. Immunohistochemistry (IHC) confirms the NHL of T-cell origin. This article is an attempt to correlate the clinical presentation and histological importance of small round cell tumors of the jaw and to discuss the differential diagnosis of small round cell tumors. Typically, a multimodal approach is employed, and the principal ancillary technique that have been found to be useful in classification is IHC. |
format | Online Article Text |
id | pubmed-7802842 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-78028422021-01-15 Non-Hodgkins lymphoma – A case report and review of literature Singaraju, Sasidhar Patel, Shubham Sharma, Ashish Singaraju, Medhini J Oral Maxillofac Pathol Case Report Lymphomas are solid tumors of the immune system and include 14% of all head and neck malignancies. Non-Hodgkin lymphomas (NHLs) are a heterogeneous group of lymphoproliferative disorders originating in B-, T-, or natural killer T-cells. They have a wide range of histological appearances and clinical features at presentation, which can make diagnosis difficult. A 58-year-old male patient presented with a 1-month history of swelling in the upper right back tooth region, which developed after extraction. On intraoral examination, there was small nodular lesion proliferation from the extracted socket. Biopsy specimen on histological examination revealed sheets of small round cells with hyperchromatic nucleus resembling lymphoblast. Immunohistochemistry (IHC) confirms the NHL of T-cell origin. This article is an attempt to correlate the clinical presentation and histological importance of small round cell tumors of the jaw and to discuss the differential diagnosis of small round cell tumors. Typically, a multimodal approach is employed, and the principal ancillary technique that have been found to be useful in classification is IHC. Wolters Kluwer - Medknow 2020 2020-09-09 /pmc/articles/PMC7802842/ /pubmed/33456242 http://dx.doi.org/10.4103/jomfp.JOMFP_271_19 Text en Copyright: © 2020 Journal of Oral and Maxillofacial Pathology http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Case Report Singaraju, Sasidhar Patel, Shubham Sharma, Ashish Singaraju, Medhini Non-Hodgkins lymphoma – A case report and review of literature |
title | Non-Hodgkins lymphoma – A case report and review of literature |
title_full | Non-Hodgkins lymphoma – A case report and review of literature |
title_fullStr | Non-Hodgkins lymphoma – A case report and review of literature |
title_full_unstemmed | Non-Hodgkins lymphoma – A case report and review of literature |
title_short | Non-Hodgkins lymphoma – A case report and review of literature |
title_sort | non-hodgkins lymphoma – a case report and review of literature |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7802842/ https://www.ncbi.nlm.nih.gov/pubmed/33456242 http://dx.doi.org/10.4103/jomfp.JOMFP_271_19 |
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