Upregulation of miR-137 Expression Suppresses Tumor Growth and Progression via Interacting with DNMT3a Through Inhibiting the PTEN/Akt Signaling in HCC

BACKGROUND: Downregulation of miR-137 regulates tumor growth in hepatocellular carcinoma (HCC). Yet, the underlying molecular mechanisms stay unclear. MATERIALS AND METHODS: miR-137 and DNA methyltransferase 3a (DNMT3a) expression levels were detected by Western blot, immunohistochemistry and qRT-PC...

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Detalles Bibliográficos
Autores principales: Wang, Jiachen, Wang, Zhao, Yuan, Jiaxiang, Wang, Qun, Shen, Xinsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7802901/
https://www.ncbi.nlm.nih.gov/pubmed/33447058
http://dx.doi.org/10.2147/OTT.S268570

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7802901/
https://www.ncbi.nlm.nih.gov/pubmed/33447058
http://dx.doi.org/10.2147/OTT.S268570

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