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GABAergic neurons are susceptible to BAX-dependent apoptosis following isoflurane exposure in the neonatal period
Exposure to volatile anesthetics during the neonatal period results in acute neuron death. Prior work suggests that apoptosis is the dominant mechanism mediating neuron death. We show that Bax deficiency blocks neuronal death following exposure to isoflurane during the neonatal period. Blocking Bax-...
Autores principales: | Slupe, Andrew M., Villasana, Laura, Wright, Kevin M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7802958/ https://www.ncbi.nlm.nih.gov/pubmed/33434191 http://dx.doi.org/10.1371/journal.pone.0238799 |
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