Association between elevated plasma aldosterone concentration and left atrial conduit function in hypertension

Aldosterone affects myocardial fibrosis and remodeling. The aim was to investigate the relationship between plasma aldosterone concentration (PAC) and left atrial (LA) function in hypertension. 148 hypertensive patients were studied. LA phasic function was evaluated by strain and strain rate imaging...

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Detalles Bibliográficos
Autores principales: Zhang, Shenglin, Gao, Xin, Wang, Dongxia, Jiang, Yinong, Liu, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803024/
https://www.ncbi.nlm.nih.gov/pubmed/33447748
http://dx.doi.org/10.1016/j.ijchy.2019.100015
Descripción
Sumario:Aldosterone affects myocardial fibrosis and remodeling. The aim was to investigate the relationship between plasma aldosterone concentration (PAC) and left atrial (LA) function in hypertension. 148 hypertensive patients were studied. LA phasic function was evaluated by strain and strain rate imaging. Patients were divided into two groups based on PAC. LA early diastolic strain and strain rate (LA(S-E) and LA(SR-E)) were lower in group II compared with group I (P ​< ​0.05). Multivariate regression analysis showed that LA(S-E) was independently related to PAC (β ​= ​−0.581, P ​< ​0.001). In conclusion, PAC is associated with LA conduit function in hypertension.

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