Association between elevated plasma aldosterone concentration and left atrial conduit function in hypertension

Aldosterone affects myocardial fibrosis and remodeling. The aim was to investigate the relationship between plasma aldosterone concentration (PAC) and left atrial (LA) function in hypertension. 148 hypertensive patients were studied. LA phasic function was evaluated by strain and strain rate imaging...

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Detalles Bibliográficos
Autores principales: Zhang, Shenglin, Gao, Xin, Wang, Dongxia, Jiang, Yinong, Liu, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803024/
https://www.ncbi.nlm.nih.gov/pubmed/33447748
http://dx.doi.org/10.1016/j.ijchy.2019.100015
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author Zhang, Shenglin
Gao, Xin
Wang, Dongxia
Jiang, Yinong
Liu, Yan
author_facet Zhang, Shenglin
Gao, Xin
Wang, Dongxia
Jiang, Yinong
Liu, Yan
author_sort Zhang, Shenglin
collection PubMed
description Aldosterone affects myocardial fibrosis and remodeling. The aim was to investigate the relationship between plasma aldosterone concentration (PAC) and left atrial (LA) function in hypertension. 148 hypertensive patients were studied. LA phasic function was evaluated by strain and strain rate imaging. Patients were divided into two groups based on PAC. LA early diastolic strain and strain rate (LA(S-E) and LA(SR-E)) were lower in group II compared with group I (P ​< ​0.05). Multivariate regression analysis showed that LA(S-E) was independently related to PAC (β ​= ​−0.581, P ​< ​0.001). In conclusion, PAC is associated with LA conduit function in hypertension.
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spelling pubmed-78030242021-01-13 Association between elevated plasma aldosterone concentration and left atrial conduit function in hypertension Zhang, Shenglin Gao, Xin Wang, Dongxia Jiang, Yinong Liu, Yan Int J Cardiol Hypertens Research Paper Aldosterone affects myocardial fibrosis and remodeling. The aim was to investigate the relationship between plasma aldosterone concentration (PAC) and left atrial (LA) function in hypertension. 148 hypertensive patients were studied. LA phasic function was evaluated by strain and strain rate imaging. Patients were divided into two groups based on PAC. LA early diastolic strain and strain rate (LA(S-E) and LA(SR-E)) were lower in group II compared with group I (P ​< ​0.05). Multivariate regression analysis showed that LA(S-E) was independently related to PAC (β ​= ​−0.581, P ​< ​0.001). In conclusion, PAC is associated with LA conduit function in hypertension. Elsevier 2019-07-02 /pmc/articles/PMC7803024/ /pubmed/33447748 http://dx.doi.org/10.1016/j.ijchy.2019.100015 Text en © 2019 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Research Paper
Zhang, Shenglin
Gao, Xin
Wang, Dongxia
Jiang, Yinong
Liu, Yan
Association between elevated plasma aldosterone concentration and left atrial conduit function in hypertension
title Association between elevated plasma aldosterone concentration and left atrial conduit function in hypertension
title_full Association between elevated plasma aldosterone concentration and left atrial conduit function in hypertension
title_fullStr Association between elevated plasma aldosterone concentration and left atrial conduit function in hypertension
title_full_unstemmed Association between elevated plasma aldosterone concentration and left atrial conduit function in hypertension
title_short Association between elevated plasma aldosterone concentration and left atrial conduit function in hypertension
title_sort association between elevated plasma aldosterone concentration and left atrial conduit function in hypertension
topic Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803024/
https://www.ncbi.nlm.nih.gov/pubmed/33447748
http://dx.doi.org/10.1016/j.ijchy.2019.100015
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