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Interamerican Society of Cardiology (IASC) position statement: Chlorthalidone vs. thiazide-type diuretics()

The Interamerican Society of Cardiology (IASC) Position Statement for hypertension management in Latin America is a practical and useful review of five different hypertension guidelines. Though, thiazide diuretics have been recommended as firstline option, the position statement needs to highlight d...

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Detalles Bibliográficos
Autores principales: Pareek, Anil, Messerli, Franz H., Saravia, Gustavo, Mehta, Ravi Tejraj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803026/
https://www.ncbi.nlm.nih.gov/pubmed/33447776
http://dx.doi.org/10.1016/j.ijchy.2020.100054
Descripción
Sumario:The Interamerican Society of Cardiology (IASC) Position Statement for hypertension management in Latin America is a practical and useful review of five different hypertension guidelines. Though, thiazide diuretics have been recommended as firstline option, the position statement needs to highlight differences within the thiazide class. Chlorthalidone is structurally and pharmacokinetically distinct from thiazide-type iuretics like hydrochlorothiazide with a longer half-life and 24-h anti-hypertensive effect. It has been shown to reduce cardiovascular morbidity and mortality in several landmark studies evaluating anti-hypertensives.