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Transgenerational Effects of Traumatic Historical Events on the Incidence of Metabolic Syndrome/ Nonalcoholic Fatty Liver Disease in the Romanian Population

Concerns for successful public health management are integrated into the core business of government-responsible institutions. Diseases associated with metabolic syndrome are very common in the Romanian population. In our study, we focused on the cardiovascular and non-alcoholic fatty liver disease...

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Autores principales: Stoica, Victor, Gardan, Daniel Adrian, Constantinescu, Ileana, Gardan, Iuliana Petronela, Calenic, Bogdan, Diculescu, Mircea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Carol Davila University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803300/
https://www.ncbi.nlm.nih.gov/pubmed/33456595
http://dx.doi.org/10.25122/jml-2020-0156
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author Stoica, Victor
Gardan, Daniel Adrian
Constantinescu, Ileana
Gardan, Iuliana Petronela
Calenic, Bogdan
Diculescu, Mircea
author_facet Stoica, Victor
Gardan, Daniel Adrian
Constantinescu, Ileana
Gardan, Iuliana Petronela
Calenic, Bogdan
Diculescu, Mircea
author_sort Stoica, Victor
collection PubMed
description Concerns for successful public health management are integrated into the core business of government-responsible institutions. Diseases associated with metabolic syndrome are very common in the Romanian population. In our study, we focused on the cardiovascular and non-alcoholic fatty liver disease (NAFLD). The article starts from the hypothesis that the increased incidence of such diseases is determined today by the cumulative effect of traumatic historical events such as the famine of 1946-47 and the communist political regime specific to the 80s and 90s. This study aims to present the arguments that indicate the correlation of economic variables whose variation can be easily determined by traumatic events that affected the economy, with variables able to measure the incidence of various diseases usually associated with metabolic syndrome or NAFLD. A series of statistical data were analyzed from the official sources available in the form of consecutive value data for the 1995-2018 period. The results highlighted a direct and strong link between the variable gross domestic product (GDP) per capita in USD, 2011 purchasing power parity (PPP) and specific incidence of circulatory, nutritional endocrine and metabolic diseases, as well as a strong and inverse link between GDP and infant’s deaths per 1000 live births. Conclusions highlight that the effects of traumatic historical events must be made aware through medical education of the population, supporting the idea according to which the incidence of various metabolic diseases is greater for the offspring of those who have actively suffered during such events.
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spelling pubmed-78033002021-01-15 Transgenerational Effects of Traumatic Historical Events on the Incidence of Metabolic Syndrome/ Nonalcoholic Fatty Liver Disease in the Romanian Population Stoica, Victor Gardan, Daniel Adrian Constantinescu, Ileana Gardan, Iuliana Petronela Calenic, Bogdan Diculescu, Mircea J Med Life Original Article Concerns for successful public health management are integrated into the core business of government-responsible institutions. Diseases associated with metabolic syndrome are very common in the Romanian population. In our study, we focused on the cardiovascular and non-alcoholic fatty liver disease (NAFLD). The article starts from the hypothesis that the increased incidence of such diseases is determined today by the cumulative effect of traumatic historical events such as the famine of 1946-47 and the communist political regime specific to the 80s and 90s. This study aims to present the arguments that indicate the correlation of economic variables whose variation can be easily determined by traumatic events that affected the economy, with variables able to measure the incidence of various diseases usually associated with metabolic syndrome or NAFLD. A series of statistical data were analyzed from the official sources available in the form of consecutive value data for the 1995-2018 period. The results highlighted a direct and strong link between the variable gross domestic product (GDP) per capita in USD, 2011 purchasing power parity (PPP) and specific incidence of circulatory, nutritional endocrine and metabolic diseases, as well as a strong and inverse link between GDP and infant’s deaths per 1000 live births. Conclusions highlight that the effects of traumatic historical events must be made aware through medical education of the population, supporting the idea according to which the incidence of various metabolic diseases is greater for the offspring of those who have actively suffered during such events. Carol Davila University Press 2020 /pmc/articles/PMC7803300/ /pubmed/33456595 http://dx.doi.org/10.25122/jml-2020-0156 Text en ©Carol Davila University Press This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/), which permits unrestricted use and redistribution provided that the original author and source are credited.
spellingShingle Original Article
Stoica, Victor
Gardan, Daniel Adrian
Constantinescu, Ileana
Gardan, Iuliana Petronela
Calenic, Bogdan
Diculescu, Mircea
Transgenerational Effects of Traumatic Historical Events on the Incidence of Metabolic Syndrome/ Nonalcoholic Fatty Liver Disease in the Romanian Population
title Transgenerational Effects of Traumatic Historical Events on the Incidence of Metabolic Syndrome/ Nonalcoholic Fatty Liver Disease in the Romanian Population
title_full Transgenerational Effects of Traumatic Historical Events on the Incidence of Metabolic Syndrome/ Nonalcoholic Fatty Liver Disease in the Romanian Population
title_fullStr Transgenerational Effects of Traumatic Historical Events on the Incidence of Metabolic Syndrome/ Nonalcoholic Fatty Liver Disease in the Romanian Population
title_full_unstemmed Transgenerational Effects of Traumatic Historical Events on the Incidence of Metabolic Syndrome/ Nonalcoholic Fatty Liver Disease in the Romanian Population
title_short Transgenerational Effects of Traumatic Historical Events on the Incidence of Metabolic Syndrome/ Nonalcoholic Fatty Liver Disease in the Romanian Population
title_sort transgenerational effects of traumatic historical events on the incidence of metabolic syndrome/ nonalcoholic fatty liver disease in the romanian population
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803300/
https://www.ncbi.nlm.nih.gov/pubmed/33456595
http://dx.doi.org/10.25122/jml-2020-0156
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