Cargando…

High serum neurofilament associates with diffuse white matter damage in MS

OBJECTIVE: To evaluate to which extent serum neurofilament light chain (NfL) increase is related to diffusion tensor imaging–MRI measurable diffuse normal-appearing white matter (NAWM) damage in MS. METHODS: Seventy-nine patients with MS and 10 healthy controls underwent MRI including diffusion tens...

Descripción completa

Detalles Bibliográficos
Autores principales:	Saraste, Maija, Bezukladova, Svetlana, Matilainen, Markus, Tuisku, Jouni, Rissanen, Eero, Sucksdorff, Marcus, Laaksonen, Sini, Vuorimaa, Anna, Kuhle, Jens, Leppert, David, Airas, Laura
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803327/ https://www.ncbi.nlm.nih.gov/pubmed/33293460 http://dx.doi.org/10.1212/NXI.0000000000000926

Ejemplares similares

Association of serum neurofilament light with microglial activation in multiple sclerosis
por: Saraste, Maija, et al.
Publicado: (2023)

Insights into disseminated MS brain pathology with multimodal diffusion tensor and PET imaging
por: Bezukladova, Svetlana, et al.
Publicado: (2020)

Natalizumab treatment reduces microglial activation in the white matter of the MS brain
por: Sucksdorff, Marcus, et al.
Publicado: (2019)

Brain TSPO-PET predicts later disease progression independent of relapses in multiple sclerosis
por: Sucksdorff, Marcus, et al.
Publicado: (2020)

Phenotyping of multiple sclerosis lesions according to innate immune cell activation using 18 kDa translocator protein-PET
por: Nylund, Marjo, et al.
Publicado: (2021)

Microglial activation, white matter tract damage, and disability in MS
por: Rissanen, Eero, et al.
Publicado: (2018)

Innate Immune Cell–Related Pathology in the Thalamus Signals a Risk for Disability Progression in Multiple Sclerosis
por: Misin, Olavi, et al.
Publicado: (2022)

TSPO-Detectable Chronic Active Lesions Predict Disease Progression in Multiple Sclerosis
por: Polvinen, Eero, et al.
Publicado: (2023)

In Vivo PET Imaging of Adenosine 2A Receptors in Neuroinflammatory and Neurodegenerative Disease
por: Vuorimaa, Anna, et al.
Publicado: (2017)

Serum neurofilament light chains in MS: Association with the Timed Up and Go
por: Allali, Gilles, et al.
Publicado: (2020)

Adenosine A(2A) receptor availability in patients with early- and moderate-stage Parkinson’s disease
por: Waggan, Imran, et al.
Publicado: (2022)

Blood neurofilament light chain at the doorstep of clinical application
por: Leppert, David, et al.
Publicado: (2019)

Blood neurofilament light as a potential endpoint in Phase 2 studies in MS
por: Sormani, Maria Pia, et al.
Publicado: (2019)

Blood neurofilament light chain as a biomarker of MS disease activity and treatment response
por: Kuhle, Jens, et al.
Publicado: (2019)

Monitoring of radiologic disease activity by serum neurofilaments in MS
por: Uher, Tomas, et al.
Publicado: (2020)

Natalizumab treatment leads to an increase in circulating CXCR3-expressing B cells
por: Saraste, Maija, et al.
Publicado: (2016)

Serum neurofilament light chain and optical coherence tomography measures in MS: A longitudinal study
por: Tavazzi, Eleonora, et al.
Publicado: (2020)

Chronic White Matter Inflammation and Serum Neurofilament Levels in Multiple Sclerosis
por: Maggi, Pietro, et al.
Publicado: (2021)

Evaluation of Microglial Activation in Multiple Sclerosis Patients Using Positron Emission Tomography
por: Airas, Laura, et al.
Publicado: (2018)

Neurofilament light chain predicts disease activity in relapsing-remitting MS
por: Varhaug, Kristin N., et al.
Publicado: (2017)

Imaging neuroinflammation in multiple sclerosis using TSPO-PET
por: Airas, Laura, et al.
Publicado: (2015)

Longitudinal analyses of serum neurofilament light and associations with obesity indices and bioelectrical impedance parameters
por: Hermesdorf, Marco, et al.
Publicado: (2022)

Association of neuronal injury blood marker neurofilament light chain with mild-to-moderate COVID-19
por: Ameres, Markus, et al.
Publicado: (2020)

Sustained reduction of serum neurofilament light chain over 7 years by alemtuzumab in early relapsing–remitting MS
por: Kuhle, Jens, et al.
Publicado: (2021)

Long-term prognostic value of longitudinal measurements of blood neurofilament levels
por: Häring, Dieter A., et al.
Publicado: (2020)

Development of an age‐adjusted model for blood neurofilament light chain
por: Harp, Christopher, et al.
Publicado: (2022)

Evaluation of neurofilament light chain in the cerebrospinal fluid and blood as a biomarker for neuronal damage in experimental pneumococcal meningitis
por: Le, Ngoc Dung, et al.
Publicado: (2020)

Serum neurofilament light chain as outcome marker for intensive care unit patients
por: Fisse, Anna Lena, et al.
Publicado: (2020)

Factors influencing serum neurofilament light chain levels in normal aging
por: Koini, Marisa, et al.
Publicado: (2021)

Evidence of polygenic regulation of the physiological presence of neurofilament light chain in human serum
por: Herrera-Rivero, Marisol, et al.
Publicado: (2023)

Neurofilament light in CSF and serum is a sensitive marker for axonal white matter injury in MS
por: Bergman, Joakim, et al.
Publicado: (2016)

Ratio and index of Neurofilament light chain indicate its origin in Guillain‐Barré Syndrome
por: Körtvelyessy, Peter, et al.
Publicado: (2020)

Blood Neurofilament Light in Progressive Multiple Sclerosis: Post Hoc Analysis of 2 Randomized Controlled Trials
por: Leppert, David, et al.
Publicado: (2022)

A Method to Combine Neurofilament Light Measurements From Blood Serum and Plasma in Clinical and Population-Based Studies
por: Rübsamen, Nicole, et al.
Publicado: (2022)

Serum neurofilament light levels in normal aging and their association with morphologic brain changes
por: Khalil, Michael, et al.
Publicado: (2020)

Plasma neurofilament light levels are associated with risk of disability in multiple sclerosis
por: Manouchehrinia, Ali, et al.
Publicado: (2020)

Early life serum neurofilament dynamics predict neurodevelopmental outcome of preterm infants
por: Goeral, Katharina, et al.
Publicado: (2021)

Serum neurofilament light and tau as prognostic markers for all-cause mortality in the elderly general population—an analysis from the MEMO study
por: Rübsamen, Nicole, et al.
Publicado: (2021)

Neurofilament light chain level is a weak risk factor for the development of MS
por: Arrambide, Georgina, et al.
Publicado: (2016)

Serum neurofilament light chain is a useful biomarker in pediatric multiple sclerosis
por: Reinert, Marie-Christine, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_77tbb0i5tmube0itqofvn543ca