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Urate, Blood Pressure, and Cardiovascular Disease: Evidence From Mendelian Randomization and Meta-Analysis of Clinical Trials

Serum urate has been implicated in hypertension and cardiovascular disease, but it is not known whether it is exerting a causal effect. To investigate this, we performed Mendelian randomization analysis using data from UK Biobank, Million Veterans Program and genome-wide association study consortia,...

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Detalles Bibliográficos
Autores principales: Gill, Dipender, Cameron, Alan C., Burgess, Stephen, Li, Xue, Doherty, Daniel J., Karhunen, Ville, Abdul-Rahim, Azmil H., Taylor-Rowan, Martin, Zuber, Verena, Tsao, Philip S., Klarin, Derek, Evangelou, Evangelos, Elliott, Paul, Damrauer, Scott M., Quinn, Terence J., Dehghan, Abbas, Theodoratou, Evropi, Dawson, Jesse, Tzoulaki, Ioanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803439/
https://www.ncbi.nlm.nih.gov/pubmed/33356394
http://dx.doi.org/10.1161/HYPERTENSIONAHA.120.16547

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