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Urate, Blood Pressure, and Cardiovascular Disease: Evidence From Mendelian Randomization and Meta-Analysis of Clinical Trials
Serum urate has been implicated in hypertension and cardiovascular disease, but it is not known whether it is exerting a causal effect. To investigate this, we performed Mendelian randomization analysis using data from UK Biobank, Million Veterans Program and genome-wide association study consortia,...
Autores principales: | Gill, Dipender, Cameron, Alan C., Burgess, Stephen, Li, Xue, Doherty, Daniel J., Karhunen, Ville, Abdul-Rahim, Azmil H., Taylor-Rowan, Martin, Zuber, Verena, Tsao, Philip S., Klarin, Derek, Evangelou, Evangelos, Elliott, Paul, Damrauer, Scott M., Quinn, Terence J., Dehghan, Abbas, Theodoratou, Evropi, Dawson, Jesse, Tzoulaki, Ioanna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803439/ https://www.ncbi.nlm.nih.gov/pubmed/33356394 http://dx.doi.org/10.1161/HYPERTENSIONAHA.120.16547 |
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