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Direct Actions of AT(1) (Type 1 Angiotensin) Receptors in Cardiomyocytes Do Not Contribute to Cardiac Hypertrophy

Activation of AT(1) (type 1 Ang) receptors stimulates cardiomyocyte hypertrophy in vitro. Accordingly, it has been suggested that regression of cardiac hypertrophy associated with renin-Ang system blockade is due to inhibition of cellular actions of Ang II in the heart, above and beyond their effect...

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Detalles Bibliográficos
Autores principales: Sparks, Matthew A., Rianto, Fitra, Diaz, Edward, Revoori, Ritika, Hoang, Thien, Bouknight, Lucas, Stegbauer, Johannes, Vivekanandan-Giri, Anuradha, Ruiz, Phillip, Pennathur, Subramaniam, Abraham, Dennis M., Gurley, Susan B., Crowley, Steven D., Coffman, Thomas M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803456/
https://www.ncbi.nlm.nih.gov/pubmed/33390039
http://dx.doi.org/10.1161/HYPERTENSIONAHA.119.14079