Cargando…

The association of Plk1 with the astrin–kinastrin complex promotes formation and maintenance of a metaphase plate

Errors in mitotic chromosome segregation can lead to DNA damage and aneuploidy, both hallmarks of cancer. To achieve synchronous error-free segregation, mitotic chromosomes must align at the metaphase plate with stable amphitelic attachments to microtubules emanating from opposing spindle poles. The...

Descripción completa

Detalles Bibliográficos
Autores principales:	Geraghty, Zoë, Barnard, Christina, Uluocak, Pelin, Gruneberg, Ulrike
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Company of Biologists Ltd 2021
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803464/ https://www.ncbi.nlm.nih.gov/pubmed/33288550 http://dx.doi.org/10.1242/jcs.251025

Ejemplares similares

The astrin–kinastrin/SKAP complex localizes to microtubule plus ends and facilitates chromosome alignment
por: Dunsch, Anja K., et al.
Publicado: (2011)

Astrin is required for the maintenance of sister chromatid cohesion and centrosome integrity
por: Thein, Kerstin H., et al.
Publicado: (2007)

PP1 promotes cyclin B destruction and the metaphase–anaphase transition by dephosphorylating CDC20
por: Bancroft, James, et al.
Publicado: (2020)

Src-mediated tyrosine phosphorylation of PRC1 and kinastrin/SKAP on the mitotic spindle
por: Morii, Mariko, et al.
Publicado: (2021)

Hypoxia-inducible factors, mTOR, and astrin constitute an integrative regulatory network in colon cancer cells
por: Saint-Martin, Abril, et al.
Publicado: (2022)

Two types of highly ordered micro- and macrochromosome arrangement in metaphase plates of butterflies (Lepidoptera)
por: Lukhtanov, Vladimir A.
Publicado: (2019)

Astrin: A Key Player in Mitosis and Cancer
por: Ying, Zhenguang, et al.
Publicado: (2020)

Aurora B kinase controls the targeting of the Astrin–SKAP complex to bioriented kinetochores
por: Schmidt, Jens C., et al.
Publicado: (2010)

PP2A-B56 opposes Mps1 phosphorylation of Knl1 and thereby promotes spindle assembly checkpoint silencing
por: Espert, Antonio, et al.
Publicado: (2014)

Astrin-SKAP complex reconstitution reveals its kinetochore interaction with microtubule-bound Ndc80
por: Kern, David M, et al.
Publicado: (2017)

Relocation of Aurora B from centromeres to the central spindle at the metaphase to anaphase transition requires MKlp2
por: Gruneberg, Ulrike, et al.
Publicado: (2004)

Molecular requirements for the inter-subunit interaction and kinetochore recruitment of SKAP and Astrin
por: Friese, Alexandra, et al.
Publicado: (2016)

Equilibration time with cryoprotectants, but not melatonin supplementation during in vitro maturation, affects viability and metaphase plate morphology of vitrified porcine mature oocytes
por: Gonzalez‐Plaza, Alejandro, et al.
Publicado: (2022)

The equatorial position of the metaphase plate ensures symmetric cell divisions
por: Tan, Chia Huei, et al.
Publicado: (2015)

The mitotic spindle protein SPAG5/Astrin connects to the Usher protein network postmitotically
por: Kersten, Ferry FJ, et al.
Publicado: (2012)

CLUH controls astrin-1 expression to couple mitochondrial metabolism to cell cycle progression
por: Schatton, Désirée, et al.
Publicado: (2022)

CCHCR1-astrin interaction promotes centriole duplication through recruitment of CEP72
por: Ying, Zhenguang, et al.
Publicado: (2022)

Kinetochore alignment within the metaphase plate is regulated by centromere stiffness and microtubule depolymerases
por: Jaqaman, Khuloud, et al.
Publicado: (2010)

Impact of Maturation and Vitrification Time of Human GV Oocytes on the Metaphase Plate Configuration
por: Peinado, Irene, et al.
Publicado: (2021)

The effect of rapamycin on bovine oocyte maturation success and metaphase telomere length maintenance
por: Kordowitzki, Pawel, et al.
Publicado: (2020)

Kinetochores attached to microtubule-ends are stabilised by Astrin bound PP1 to ensure proper chromosome segregation
por: Conti, Duccio, et al.
Publicado: (2019)

Kinase PLK1 regulates the disassembly of the lateral elements and the assembly of the inner centromere during the diakinesis/metaphase I transition in male mouse meiosis
por: Gómez, Rocío, et al.
Publicado: (2023)

CENP-meta, an Essential Kinetochore Kinesin Required for the Maintenance of Metaphase Chromosome Alignment in Drosophila
por: Yucel, Jennifer K., et al.
Publicado: (2000)

PI 3-kinase-dependent phosphorylation of Plk1–Ser99 promotes association with 14-3-3γ and is required for metaphase–anaphase transition
por: Kasahara, Kousuke, et al.
Publicado: (2013)

Metaphase Spindle Assembly
por: Kapoor, Tarun M.
Publicado: (2017)

A new way of describing meiosis that uses fractal dimension to predict metaphase I
por: Ross, Cynthia M.
Publicado: (2005)

Advanced mare age impairs the ability of in vitro‐matured oocytes to correctly align chromosomes on the metaphase plate
por: Rizzo, M., et al.
Publicado: (2018)

Counteraction between Astrin-PP1 and Cyclin-B-CDK1 pathways protects chromosome-microtubule attachments independent of biorientation
por: Song, Xinhong, et al.
Publicado: (2021)

STUDIES ON THE ISOLATION OF METAPHASE CHROMOSOMES
por: ChoraŻy, M., et al.
Publicado: (1963)

Why metaphase chromosomes wander
por: Leslie, Mitch
Publicado: (2013)

Helical coiling of metaphase chromatids
por: Kubalová, Ivona, et al.
Publicado: (2023)

Progerin impairs chromosome maintenance by depleting CENP-F from metaphase kinetochores in Hutchinson-Gilford progeria fibroblasts
por: Eisch, Veronika, et al.
Publicado: (2016)

Dynamin regulates metaphase furrow formation and plasma membrane compartmentalization in the syncytial Drosophila embryo
por: Rikhy, Richa, et al.
Publicado: (2015)

Requirement for PLK1 kinase activity in the maintenance of a robust spindle assembly checkpoint
por: O'Connor, Aisling, et al.
Publicado: (2015)

Clinical benefit of metaphase I oocytes
por: Vanhoutte, Leen, et al.
Publicado: (2005)

The kinetochore is part of the metaphase chromosome scaffold
Publicado: (1984)

Architecture of metaphase chromosomes and chromosome scaffolds
Publicado: (1983)

A postprophase topoisomerase II-dependent chromatid core separation step in the formation of metaphase chromosomes
Publicado: (1995)

Spindle Formation in the Mouse Embryo Requires Plk4 in the Absence of Centrioles
por: Coelho, Paula A., et al.
Publicado: (2013)

PLK1 Interacts and Phosphorylates Axin That Is Essential for Proper Centrosome Formation
por: Ruan, Ka, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_8bvlfpp3i1q2hurltekfrpei5e