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Novel Orally Administered Recombinant Anti-TNF Alpha Fusion Protein for the Treatment of Ulcerative Colitis: Results From a Phase 2a Clinical Trial

BACKGROUND AND OBJECTIVE: OPRX-106 is an orally administered BY2 plant cell-expressing recombinant TNF fusion protein (TNFR). Oral administration of OPRX-106 was shown to be safe and effective in inducing favorable anti-inflammatory immune modulation in humans. The current study was aimed at determi...

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Detalles Bibliográficos
Autores principales: Almon, Einat, Shaaltiel, Yoseph, Sbeit, Wisam, Fich, Alex, Schwartz, Doron, Waterman, Mattitiahu, Szlaifer, Mali, Reuveni, Hadar, Amit-Cohen, Bat-chen, Alon, Sari, Chertkoff, Raul, Paz, Alona, Ilan, Yaron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803480/
https://www.ncbi.nlm.nih.gov/pubmed/32501868
http://dx.doi.org/10.1097/MCG.0000000000001314

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