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miRNA-122-5p stimulates the proliferation and DNA synthesis and inhibits the early apoptosis of human spermatogonial stem cells by targeting CBL and competing with lncRNA CASC7
Epigenetic regulators of human spermatogonia stem cells (SSCs) remain largely unknown. We found that miRNA-122-5p was upregulated in human spermatogonia from obstructive azoospermia (OA) patients compared with non-obstructive azoospermia (NOA). MiRNA-122-5p stimulated the proliferation and DNA synth...
Autores principales: | Zhou, Fan, Chen, Wei, Cui, Yinghong, Liu, Bang, Yuan, Qingqing, Li, Zheng, He, Zuping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803487/ https://www.ncbi.nlm.nih.gov/pubmed/33231565 http://dx.doi.org/10.18632/aging.104158 |
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