Postprandial triglyceride-rich lipoproteins-induced premature senescence of adipose-derived mesenchymal stem cells via the SIRT1/p53/Ac-p53/p21 axis through oxidative mechanism

The accumulation of senescent adipose-derived mesenchymal stem cells (AMSCs) in subcutaneous white adipose tissue (WAT) is the main cause for the deterioration of WAT and the subsequent age-related disorders in obesity. The number of AMSCs staining positively for senescence-associated-β-galactosidas...

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Detalles Bibliográficos
Autores principales: Xiang, Qun-yan, Tian, Feng, Du, Xiao, Xu, Jin, Zhu, Li-yuan, Guo, Li-ling, Wen, Tie, Liu, You-shuo, Liu, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803527/
https://www.ncbi.nlm.nih.gov/pubmed/33316776
http://dx.doi.org/10.18632/aging.202298

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803527/
https://www.ncbi.nlm.nih.gov/pubmed/33316776
http://dx.doi.org/10.18632/aging.202298

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