Aberrant RhoA activation in macrophages increases senescence-associated secretory phenotypes and ectopic calcification in muscular dystrophic mice

Duchenne Muscular Dystrophy (DMD) patients often suffer from both muscle wasting and osteoporosis. Our previous studies have revealed reduced regeneration potential in skeletal muscle and bone, concomitant with ectopic calcification of soft tissues in double knockout (dKO, dystrophin-/-; utrophin-/-...

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Detalles Bibliográficos
Autores principales: Mu, Xiaodong, Lin, Chi-Yi, Hambright, William S., Tang, Ying, Ravuri, Sudheer, Lu, Aiping, Matre, Polina, Chen, Wanqun, Gao, Xueqin, Cui, Yan, Zhong, Ling, Wang, Bing, Huard, Johnny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803538/
https://www.ncbi.nlm.nih.gov/pubmed/33361519
http://dx.doi.org/10.18632/aging.202413

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