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Subanesthetic isoflurane abates ROS-activated MAPK/NF-κB signaling to repress ischemia-induced microglia inflammation and brain injury
Isoflurane (ISO) elicits protective effects on ischemia-induced brain injury. We investigated whether sub-anesthetic (0.7%) ISO post-conditioning attenuates the inflammation and apoptosis in oxygen-glucose deprivation (OGD)-insulted co-cultures (microglia and neurons) in vitro and the brain injury o...
Autores principales: | Yao, Zhiqiang, Liu, Ningning, Zhu, Xiaoshan, Wang, Ling, Zhao, Yali, Liu, Qinqin, Gao, Chunfang, Li, Juntang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803578/ https://www.ncbi.nlm.nih.gov/pubmed/33373319 http://dx.doi.org/10.18632/aging.202349 |
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