Hepatotoxicity prevention in Acetaminophen-induced HepG2 cells by red betel (Piper crocatum Ruiz and Pav) extract from Indonesia via antioxidant, anti-inflammatory, and anti-necrotic

Acetaminophen (APAP) is a widely used analgesic, but it may cause liver injury (hepatotoxicity) via oxidative stress that induced by N-acetyl-p-benzoquinone imine (NAPQI) in long term usage or overdose. Multiple inflammatory mediators were also found to contribute for this effect. Many medicinal pla...

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Detalles Bibliográficos
Autores principales: Ginting, Chrismis Novalinda, Lister, I Nyoman Ehrich, Girsang, Ermi, Widowati, Wahyu, Yusepany, Dewani Tediana, Azizah, Alya Mardhotillah, Kusuma, Hanna Sari Widya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803640/
https://www.ncbi.nlm.nih.gov/pubmed/33474504
http://dx.doi.org/10.1016/j.heliyon.2020.e05620

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803640/
https://www.ncbi.nlm.nih.gov/pubmed/33474504
http://dx.doi.org/10.1016/j.heliyon.2020.e05620

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