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Hepatotoxicity prevention in Acetaminophen-induced HepG2 cells by red betel (Piper crocatum Ruiz and Pav) extract from Indonesia via antioxidant, anti-inflammatory, and anti-necrotic
Acetaminophen (APAP) is a widely used analgesic, but it may cause liver injury (hepatotoxicity) via oxidative stress that induced by N-acetyl-p-benzoquinone imine (NAPQI) in long term usage or overdose. Multiple inflammatory mediators were also found to contribute for this effect. Many medicinal pla...
Autores principales: | Ginting, Chrismis Novalinda, Lister, I Nyoman Ehrich, Girsang, Ermi, Widowati, Wahyu, Yusepany, Dewani Tediana, Azizah, Alya Mardhotillah, Kusuma, Hanna Sari Widya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803640/ https://www.ncbi.nlm.nih.gov/pubmed/33474504 http://dx.doi.org/10.1016/j.heliyon.2020.e05620 |
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