Cargando…

Le Carbone prevents liver damage in non-alcoholic steatohepatitis-hepatocellular carcinoma mouse model via AMPKα-SIRT1 signaling pathway activation

Le Carbone (LC), a fiber-enriched activated charcoal dietary supplement, claimed to be effective against inflammation associated with colitis, trimethylaminuria, and sclerosis. The study aimed to investigate the underlying mechanisms of LC to protect liver damage and its progression in non-alcoholic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Afrin, Mst. Rejina, Arumugam, Somasundaram, Pitchaimani, Vigneshwaran, Karuppagounder, Vengadeshprabhu, Thandavarayan, Rajarajan Amirthalingam, Harima, Meilei, Hossain, Chowdhury Faiz, Suzuki, Kenji, Sone, Hirohito, Matsubayashi, Yasuhiro, Watanabe, Kenichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803657/ https://www.ncbi.nlm.nih.gov/pubmed/33490669 http://dx.doi.org/10.1016/j.heliyon.2020.e05888

Ejemplares similares

Pruni cortex ameliorates skin inflammation possibly through HMGB1-NFκB pathway in house dust mite induced atopic dermatitis NC/Nga transgenic mice
por: Watanabe, Kenichi, et al.
Publicado: (2015)

Nootropic activity of acetaminophen against colchicine induced cognitive impairment in rats
por: Pitchaimani, Vigneshwaran, et al.
Publicado: (2012)

Modulation of Macrophage Polarization and HMGB1-TLR2/TLR4 Cascade Plays a Crucial Role for Cardiac Remodeling in Senescence-Accelerated Prone Mice
por: Karuppagounder, Vengadeshprabhu, et al.
Publicado: (2016)

Carvedilol Attenuates Inflammatory-Mediated Cardiotoxicity in Daunorubicin-Induced Rats
por: Sari, Flori R., et al.
Publicado: (2011)

Curcumin ameliorates streptozotocin-induced liver damage through modulation of endoplasmic reticulum stress-mediated apoptosis in diabetic rats
por: Afrin, R., et al.
Publicado: (2015)

SARS–CoV-2 Mediated Hyperferritinemia and Cardiac Arrest: Preliminary Insights
por: VasanthiDharmalingam, Prakash, et al.
Publicado: (2021)

3,4-Dihydroxybenzalacetone (DBL) Prevents Aging-Induced Myocardial Changes in Senescence-Accelerated Mouse-Prone 8 (SAMP8) Mice
por: Giridharan, Vijayasree V., et al.
Publicado: (2020)

Beneficial effects of edaravone, a novel antioxidant, in rats with dilated cardiomyopathy
por: Arumugam, Somasundaram, et al.
Publicado: (2012)

Small molecule disruption of G protein βγ subunit signaling reprograms human macrophage phenotype and prevents autoimmune myocarditis in rats
por: Karuppagounder, Vengadeshprabhu, et al.
Publicado: (2018)

Curcumin ameliorates macrophage infiltration by inhibiting NF-κB activation and proinflammatory cytokines in streptozotocin induced-diabetic nephropathy
por: Soetikno, Vivian, et al.
Publicado: (2011)

Antioxidant Formulae, Shengmai San, and LingGuiZhuGanTang, Prevent MPTP Induced Brain Dysfunction and Oxidative Damage in Mice
por: Giridharan, Vijayasree Vayalanellore, et al.
Publicado: (2015)

Modulation of endoplasmic reticulum stress and cardiomyocyte apoptosis by mulberry leaf diet in experimental autoimmune myocarditis rats
por: Arumugam, Somasundaram, et al.
Publicado: (2012)

Carvedilol-Afforded Protection against Daunorubicin-Induced Cardiomyopathic Rats In Vivo: Effects on Cardiac Fibrosis and Hypertrophy
por: Arozal, Wawaimuli, et al.
Publicado: (2011)

Oral toxicity of arjunolic acid on hematological, biochemical and histopathological investigations in female Sprague Dawley rats
por: Aamir, Khurram, et al.
Publicado: (2019)

Small Engine, Big Power: MicroRNAs as Regulators of Cardiac Diseases and Regeneration
por: Joladarashi, Darukeshwara, et al.
Publicado: (2014)

The Role of Carvedilol in the Treatment of Dilated and Anthracyclines-Induced Cardiomyopathy
por: Watanabe, Kenichi, et al.
Publicado: (2011)

Role of Differential Signaling Pathways and Oxidative Stress in Diabetic Cardiomyopathy
por: Watanabe, Kenichi, et al.
Publicado: (2010)

Effect of heat-moisture treated brown rice crackers on postprandial flow-mediated dilation in adults with mild endothelial dysfunction
por: Watanabe, Kenichi, et al.
Publicado: (2022)

Schisandrin B Prevents Doxorubicin Induced Cardiac Dysfunction by Modulation of DNA Damage, Oxidative Stress and Inflammation through Inhibition of MAPK/p53 Signaling
por: Thandavarayan, Rajarajan A., et al.
Publicado: (2015)

In search of suitable extraction technique for large scale commercial production of bioactive fraction for the treatment of diabetes: The case Diospyros melanoxylon Roxb.
por: Harun Al Rashid, Md., et al.
Publicado: (2018)

Aspiration-assisted bioprinting of the osteochondral interface
por: Ayan, Bugra, et al.
Publicado: (2020)

Early Gβγ-GRK2 Inhibition Ameliorates Osteoarthritis Development by Simultaneous Anti-Inflammatory and Chondroprotective Effects
por: Karuppagounder, Vengadeshprabhu, et al.
Publicado: (2022)

Schisandrin B Ameliorates ICV-Infused Amyloid β Induced Oxidative Stress and Neuronal Dysfunction through Inhibiting RAGE/NF-κB/MAPK and Up-Regulating HSP/Beclin Expression
por: Giridharan, Vijayasree V., et al.
Publicado: (2015)

Olmesartan, an AT(1) Antagonist, Attenuates Oxidative Stress, Endoplasmic Reticulum Stress and Cardiac Inflammatory Mediators in Rats with Heart Failure Induced by Experimental Autoimmune Myocarditis
por: Sukumaran, Vijayakumar, et al.
Publicado: (2011)

The efficacy and safety of first-line anti-seizure medications as substitution therapy for children with drug-resistant epilepsy: a randomized controlled trial protocol
por: Perdani, Roro Rukmi Windi, et al.
Publicado: (2023)

BDMC protects AD in vitro via AMPK and SIRT1
por: Xu, Chenlin, et al.
Publicado: (2020)

Transcript shortening via alternative polyadenylation promotes gene expression during fracture healing
por: Khajuria, Deepak Kumar, et al.
Publicado: (2023)

Specific Sirt1 Activator-mediated Improvement in Glucose Homeostasis Requires Sirt1-Independent Activation of AMPK
por: Park, Sung-Jun, et al.
Publicado: (2017)

Irisin enhances longevity by boosting SIRT1, AMPK, autophagy and telomerase
por: Sánchez, Begoña, et al.
Publicado: (2022)

Obesity-induced miR-802 directly targets AMPK and promotes nonalcoholic steatohepatitis in mice
por: Sun, Hao, et al.
Publicado: (2022)

Metformin Alleviates Steatohepatitis in Diet-Induced Obese Mice in a SIRT1-Dependent Way
por: Guo, Wan-rong, et al.
Publicado: (2021)

ALDH2 Inhibition Potentiates High Glucose Stress-Induced Injury in Cultured Cardiomyocytes
por: Pan, Guodong, et al.
Publicado: (2016)

SIRT1 Takes a Backseat to AMPK in the Regulation of Insulin Sensitivity by Resveratrol
por: Fullerton, Morgan D., et al.
Publicado: (2010)

Resveratrol-Activated AMPK/SIRT1/Autophagy in Cellular Models of Parkinson's Disease
por: Wu, Yuncheng, et al.
Publicado: (2011)

The hepatic AMPK-TET1-SIRT1 axis regulates glucose homeostasis
por: Zhang, Chunbo, et al.
Publicado: (2021)

The sex steroid precursor dehydroepiandrosterone prevents nonalcoholic steatohepatitis by activating the AMPK pathway mediated by GPR30
por: Li, Longlong, et al.
Publicado: (2021)

MKP1 promotes nonalcoholic steatohepatitis by suppressing AMPK activity through LKB1 nuclear retention
por: Qiu, Bin, et al.
Publicado: (2023)

STK35 Gene Therapy Attenuates Endothelial Dysfunction and Improves Cardiac Function in Diabetes
por: Joladarashi, Darukeshwara, et al.
Publicado: (2022)

An In Vitro Platform to Study Reversible Endothelial-to-Mesenchymal Transition
por: Krishnamoorthi, Muthu Kumar, et al.
Publicado: (2022)

Quercetin and AMPK: A Dynamic Duo in Alleviating MG-Induced Inflammation via the AMPK/SIRT1/NF-κB Pathway
por: Lu, Ziyin, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_dq9c6qerbih213cfrff3rqdjaq