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CYP3A4 mediated pharmacokinetics drug interaction potential of Maha-Yogaraj Gugglu and E, Z guggulsterone

Maha yogaraja guggulu (MYG) is a classical herbomineral polyherbal formulation being widely used since centuries. The aim of this study was to investigate the effect of MYG formulation and its major constituents E & Z guggulsterone on CYP3A4 mediated metabolism. In vitro inhibition of MYG and Gu...

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Detalles Bibliográficos
Autores principales: Sabarathinam, Sarvesh, Rajappan Chandra, Satish Kumar, Thangavel Mahalingam, Vijayakumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803744/
https://www.ncbi.nlm.nih.gov/pubmed/33436877
http://dx.doi.org/10.1038/s41598-020-80595-5