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Familial Mediterranean fever-related miR-197-3p targets IL1R1 gene and modulates inflammation in monocytes and synovial fibroblasts

Familial Mediterranean fever (FMF); is an autosomal recessively inherited autoinflammatory disease caused by the mutations in the Mediterranean Fever (MEFV) gene. Recent studies have shown that epigenetic control mechanisms, particularly non-coding RNAs, may play a role in the pathogenesis of autoin...

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Detalles Bibliográficos
Autores principales: Akkaya-Ulum, Yeliz Z., Akbaba, Tayfun Hilmi, Tavukcuoglu, Zeynep, Chae, Jae Jin, Yilmaz, Engin, Ozen, Seza, Balci-Peynircioglu, Banu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803773/
https://www.ncbi.nlm.nih.gov/pubmed/33436947
http://dx.doi.org/10.1038/s41598-020-80097-4