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Evaluation for pharmacokinetic exposure of cytotoxic anticancer drugs in elderly patients receiving (R-)CHOP therapy

(R-)miniCHOP therapy, which delivers approximately half-doses of the (R-)CHOP regimen, has shown efficacy and safety in patients who are more than 80 years old. This study aimed to compare the area under the plasma concentration–time curves (AUCs) of vincristine (VCR), doxorubicin (DXR), and cycloph...

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Detalles Bibliográficos
Autores principales:	Nakagawa, Junichi, Takahata, Takenori, Hyodo, Rui, Chen, Yu, Hasui, Kengo, Sasaki, Kota, Saito, Kensuke, Ueno, Kayo, Hosoi, Kazuhiro, Terui, Kazufumi, Sato, Atsushi, Niioka, Takenori
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803984/ https://www.ncbi.nlm.nih.gov/pubmed/33436910 http://dx.doi.org/10.1038/s41598-020-80706-2

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