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Uraemic toxins impair skeletal muscle regeneration by inhibiting myoblast proliferation, reducing myogenic differentiation, and promoting muscular fibrosis
Uraemic toxins increase in serum parallel to a decline in the glomerular filtration rate and the development of sarcopenia in patients with chronic kidney disease (CKD). This study analyses the role of uraemic toxins in sarcopenia at different stages of CKD, evaluating changes in the muscular regene...
Autores principales: | Alcalde-Estévez, Elena, Sosa, Patricia, Asenjo-Bueno, Ana, Plaza, Patricia, Olmos, Gemma, Naves-Díaz, Manuel, Rodríguez-Puyol, Diego, López-Ongil, Susana, Ruiz-Torres, María P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7804102/ https://www.ncbi.nlm.nih.gov/pubmed/33436654 http://dx.doi.org/10.1038/s41598-020-79186-1 |
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