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Identification of significantly mutated subnetworks in the breast cancer genome

Recent studies showed that somatic cancer mutations target genes that are in specific signaling and cellular pathways. However, in each patient only a few of the pathway genes are mutated. Current approaches consider only existing pathways and ignore the topology of the pathways. For this reason, ne...

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Detalles Bibliográficos
Autores principales: Ajwad, Rasif, Domaratzki, Michael, Liu, Qian, Feizi, Nikta, Hu, Pingzhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7804148/
https://www.ncbi.nlm.nih.gov/pubmed/33436820
http://dx.doi.org/10.1038/s41598-020-80204-5