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Prediction of kinase inhibitors binding modes with machine learning and reduced descriptor sets
Protein kinases are receiving wide research interest, from drug perspective, due to their important roles in human body. Available kinase-inhibitor data, including crystallized structures, revealed many details about the mechanism of inhibition and binding modes. The understanding and analysis of th...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7804204/ https://www.ncbi.nlm.nih.gov/pubmed/33436888 http://dx.doi.org/10.1038/s41598-020-80758-4 |